Prevalence and risk factors of lower limb amputations in patients with diabetic foot ulcers : A systematic review and meta-analysis

Copyright © 2022 Diabetes India. Published by Elsevier Ltd. All rights reserved..

BACKGROUND AND AIMS: The study aimed at determining prevalence and risk factors (RFs) of diabetic lower limb amputations (LLAs).

METHODS: Electronic databases including PubMed, Medline, Web of Science, and Cochrane Library were searched from January 2003 to April 2021.

RESULTS: Sixteen full-text published studies were reviewed. The prevalence of LLAs stood as high as 66%, with a combined prevalence of 19% (95% CI 10-29) using the random-effects model. The most prominent RFs for LLA were duration of diabetes mellitus (DM), age, renal impairment, and ethnic minority. Amongst Australians, Indigenous background is strongly associated with increased risk of the diabetic foot (DF) LLA.

CONCLUSIONS: LLAs are considerably prevalent amongst patients with the DF and occur at even higher rates in patients with multimorbidity.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:16

Enthalten in:

Diabetes & metabolic syndrome - 16(2022), 2 vom: 15. Feb., Seite 102397

Sprache:

Englisch

Beteiligte Personen:

Rodrigues, Beverly T [VerfasserIn]
Vangaveti, Venkat N [VerfasserIn]
Urkude, Ravindra [VerfasserIn]
Biros, Erik [VerfasserIn]
Malabu, Usman H [VerfasserIn]

Links:

Volltext

Themen:

Amputations
Diabetic foot ulcers
Journal Article
Meta-Analysis
Prevalence
Risk factors
Systematic Review

Anmerkungen:

Date Completed 31.03.2022

Date Revised 07.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.dsx.2022.102397

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM336202849