Prevalence and risk factors of lower limb amputations in patients with diabetic foot ulcers : A systematic review and meta-analysis
Copyright © 2022 Diabetes India. Published by Elsevier Ltd. All rights reserved..
BACKGROUND AND AIMS: The study aimed at determining prevalence and risk factors (RFs) of diabetic lower limb amputations (LLAs).
METHODS: Electronic databases including PubMed, Medline, Web of Science, and Cochrane Library were searched from January 2003 to April 2021.
RESULTS: Sixteen full-text published studies were reviewed. The prevalence of LLAs stood as high as 66%, with a combined prevalence of 19% (95% CI 10-29) using the random-effects model. The most prominent RFs for LLA were duration of diabetes mellitus (DM), age, renal impairment, and ethnic minority. Amongst Australians, Indigenous background is strongly associated with increased risk of the diabetic foot (DF) LLA.
CONCLUSIONS: LLAs are considerably prevalent amongst patients with the DF and occur at even higher rates in patients with multimorbidity.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2022 |
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Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
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Enthalten in: |
Diabetes & metabolic syndrome - 16(2022), 2 vom: 15. Feb., Seite 102397 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Rodrigues, Beverly T [VerfasserIn] |
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Links: |
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Themen: |
Amputations |
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Anmerkungen: |
Date Completed 31.03.2022 Date Revised 07.12.2022 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1016/j.dsx.2022.102397 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM336202849 |
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500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Copyright © 2022 Diabetes India. Published by Elsevier Ltd. All rights reserved. | ||
520 | |a BACKGROUND AND AIMS: The study aimed at determining prevalence and risk factors (RFs) of diabetic lower limb amputations (LLAs) | ||
520 | |a METHODS: Electronic databases including PubMed, Medline, Web of Science, and Cochrane Library were searched from January 2003 to April 2021 | ||
520 | |a RESULTS: Sixteen full-text published studies were reviewed. The prevalence of LLAs stood as high as 66%, with a combined prevalence of 19% (95% CI 10-29) using the random-effects model. The most prominent RFs for LLA were duration of diabetes mellitus (DM), age, renal impairment, and ethnic minority. Amongst Australians, Indigenous background is strongly associated with increased risk of the diabetic foot (DF) LLA | ||
520 | |a CONCLUSIONS: LLAs are considerably prevalent amongst patients with the DF and occur at even higher rates in patients with multimorbidity | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Meta-Analysis | |
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650 | 4 | |a Diabetic foot ulcers | |
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700 | 1 | |a Malabu, Usman H |e verfasserin |4 aut | |
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