Perception and practice of self-medication with antibiotics among medical students in Sudanese universities : A cross-sectional study
INTRODUCTION: The benefits of antibiotics are under threat by self-medication, which culminated in economic burdening of developing countries, treatment failures, the emergence of antibiotic-resistant strains of bacteria and an increased probability of exposure and infection of the general population by antibiotic-resistant bacterial strains.
OBJECTIVES: This study aimed to evaluate the knowledge and attitude of medical students in Sudan towards the use of antibiotics, the prevalence of self-medication with antibiotics among medical students in Sudan and to identify risk factors which promote self-medication with antibiotics.
MATERIALS AND METHODS: This was a cross-sectional, descriptive and institution-based study, between November 2020 and May 2021. 1,110 medical students were selected by multistage cluster sampling. Logistic regression was used to identify risk factors of self-medication with antibiotics among the study participants.
RESULTS: The median knowledge score was 7 out of a maximum of 10 (IQR: 5-8). A moderately positive attitude was observed among the participants (Median: 7/10; IQR: 6-8). Knowledge and attitude scores were significantly associated with academic year and monthly allowance (p < 0.05). 675 (60.8%) self-medicated with antibiotics within the previous 12 months, mostly from community pharmacies (321/675; 47.5%). Antibiotics were most commonly used to treat respiratory tract infections (38.1%) and cough (30.4%). Chi-square analysis demonstrated that self-medication with antibiotics was significantly associated with gender, year of study and monthly income.
CONCLUSIONS: Undergraduate medical students had moderate knowledge and attitude towards antibiotic use and antibiotic resistance, and an alarmingly high prevalence of self-medication with antibiotics. This highlights the urgent need for tighter legislation regarding the sales of antibiotics in community pharmacies by the state and federal health ministries.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:17 |
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| Enthalten in: |
PloS one - 17(2022), 1 vom: 06., Seite e0263067 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Elmahi, Osman Kamal Osman [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-Bacterial Agents |
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| Anmerkungen: |
Date Completed 21.02.2022 Date Revised 21.02.2022 published: Electronic-eCollection Citation Status MEDLINE |
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| doi: |
10.1371/journal.pone.0263067 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM336155603 |
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| 100 | 1 | |a Elmahi, Osman Kamal Osman |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Perception and practice of self-medication with antibiotics among medical students in Sudanese universities |b A cross-sectional study |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a INTRODUCTION: The benefits of antibiotics are under threat by self-medication, which culminated in economic burdening of developing countries, treatment failures, the emergence of antibiotic-resistant strains of bacteria and an increased probability of exposure and infection of the general population by antibiotic-resistant bacterial strains | ||
| 520 | |a OBJECTIVES: This study aimed to evaluate the knowledge and attitude of medical students in Sudan towards the use of antibiotics, the prevalence of self-medication with antibiotics among medical students in Sudan and to identify risk factors which promote self-medication with antibiotics | ||
| 520 | |a MATERIALS AND METHODS: This was a cross-sectional, descriptive and institution-based study, between November 2020 and May 2021. 1,110 medical students were selected by multistage cluster sampling. Logistic regression was used to identify risk factors of self-medication with antibiotics among the study participants | ||
| 520 | |a RESULTS: The median knowledge score was 7 out of a maximum of 10 (IQR: 5-8). A moderately positive attitude was observed among the participants (Median: 7/10; IQR: 6-8). Knowledge and attitude scores were significantly associated with academic year and monthly allowance (p < 0.05). 675 (60.8%) self-medicated with antibiotics within the previous 12 months, mostly from community pharmacies (321/675; 47.5%). Antibiotics were most commonly used to treat respiratory tract infections (38.1%) and cough (30.4%). Chi-square analysis demonstrated that self-medication with antibiotics was significantly associated with gender, year of study and monthly income | ||
| 520 | |a CONCLUSIONS: Undergraduate medical students had moderate knowledge and attitude towards antibiotic use and antibiotic resistance, and an alarmingly high prevalence of self-medication with antibiotics. This highlights the urgent need for tighter legislation regarding the sales of antibiotics in community pharmacies by the state and federal health ministries | ||
| 650 | 4 | |a Clinical Trial | |
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| 700 | 1 | |a Musa, Reem Abdalla Elsiddig |e verfasserin |4 aut | |
| 700 | 1 | |a Shareef, Ahd Alaaeldin Hussain |e verfasserin |4 aut | |
| 700 | 1 | |a Omer, Mohammed Eltahier Abdalla |e verfasserin |4 aut | |
| 700 | 1 | |a Elmahi, Mugahid Awad Mohamed |e verfasserin |4 aut | |
| 700 | 1 | |a Altamih, Randa Ahmed Abdalrheem |e verfasserin |4 aut | |
| 700 | 1 | |a Mohamed, Rayan Ibrahim Hamid |e verfasserin |4 aut | |
| 700 | 1 | |a Alsadig, Tagwa Faisal Mohamed |e verfasserin |4 aut | |
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