Generation and characterization of human induced pluripotent stem cells (iPSCs) from three individuals without age-related macular degeneration
Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved..
Age-related macular degeneration (AMD) is a major cause of vision loss among the elderly in the Western world. AMD is multifactorial eye disease with a strong genetic contribution. Here, we report the generation and characterization of induced pluripotent stem cells (iPSCs) derived from peripheral blood mononuclear cells of three individuals above 70 years of age without AMD. These cell lines were generated to serve as control lines for cellular studies investigating the disease mechanisms and developing therapeutic interventions for AMD.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:60 |
|---|---|
| Enthalten in: |
Stem cell research - 60(2022) vom: 15. Apr., Seite 102670 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Koolen, Louet [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 15.04.2022 Date Revised 15.04.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.scr.2022.102670 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM336125798 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM336125798 | ||
| 003 | DE-627 | ||
| 005 | 20231225231428.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.scr.2022.102670 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1120.xml |
| 035 | |a (DE-627)NLM336125798 | ||
| 035 | |a (NLM)35078129 | ||
| 035 | |a (PII)S1873-5061(22)00019-8 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Koolen, Louet |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Generation and characterization of human induced pluripotent stem cells (iPSCs) from three individuals without age-related macular degeneration |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 15.04.2022 | ||
| 500 | |a Date Revised 15.04.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved. | ||
| 520 | |a Age-related macular degeneration (AMD) is a major cause of vision loss among the elderly in the Western world. AMD is multifactorial eye disease with a strong genetic contribution. Here, we report the generation and characterization of induced pluripotent stem cells (iPSCs) derived from peripheral blood mononuclear cells of three individuals above 70 years of age without AMD. These cell lines were generated to serve as control lines for cellular studies investigating the disease mechanisms and developing therapeutic interventions for AMD | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 700 | 1 | |a Gagliardi, Giuliana |e verfasserin |4 aut | |
| 700 | 1 | |a Ten Brink, Sofie C A |e verfasserin |4 aut | |
| 700 | 1 | |a de Breuk, Anita |e verfasserin |4 aut | |
| 700 | 1 | |a Heesterbeek, Thomas J |e verfasserin |4 aut | |
| 700 | 1 | |a Hoyng, Carel B |e verfasserin |4 aut | |
| 700 | 1 | |a Albert, Silvia |e verfasserin |4 aut | |
| 700 | 1 | |a den Hollander, Anneke I |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Stem cell research |d 2007 |g 60(2022) vom: 15. Apr., Seite 102670 |w (DE-627)NLM18622009X |x 1876-7753 |7 nnns |
| 773 | 1 | 8 | |g volume:60 |g year:2022 |g day:15 |g month:04 |g pages:102670 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.scr.2022.102670 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 60 |j 2022 |b 15 |c 04 |h 102670 | ||