Effect of hybrid FES exercise on body composition during the sub-acute phase of spinal cord injury
OBJECTIVES: To determine the Effect of Hybrid functional electrically stimulated (FES) Exercise on Body Composition during the Sub-acute Phase of Spinal Cord Injury (SCI).
DESIGN: Randomized Clinical Trial.
SETTING: Rehabilitation Hospital.
PARTICIPANTS: Patients within sub-acute phase (3-24 months) of SCI.
INTERVENTIONS: We investigated if high-intensity exercise training via the addition of functional electrically stimulated (FES) leg muscles, provides sufficient stimulus to mitigate against body composition changes in the sub-acute phase after SCI.
MAIN OUTCOME MEASURES: We explored potential effects of FES row training (FESRT) on body fat gain, lean mass loss, and cardiometabolic parameters and compared the effects of 6-month of FESRT (n = 18) to standard of care (SOC, n = 13). Those in SOC were crossed over to FESRT.
RESULTS: FESRT resulted in greater exercise capacity and a tendency for lesser total body fat accumulation with a significant increase in total and leg lean mass (p<0.05). In addition pelvis and total bone mineral density declines were significantly less (p<0.05). Compared to SOC, FESRT did not lead to any significant difference in insulin sensitivity or serum lipids. However, HbA1C levels were significantly decreased in SOC participants who crossed over to 6-month FESRT.
CONCLUSION: FESRT early after SCI provides a sufficient stimulus to mitigate against detrimental body composition changes. This may lead to prevention of losses in lean mass, including bone.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:17 |
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| Enthalten in: |
PloS one - 17(2022), 1 vom: 01., Seite e0262864 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Afshari, Khashayar [VerfasserIn] |
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| Links: |
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| Themen: |
Comparative Study |
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| Anmerkungen: |
Date Completed 21.02.2022 Date Revised 21.02.2022 published: Electronic-eCollection Citation Status MEDLINE |
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| doi: |
10.1371/journal.pone.0262864 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM33607882X |
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| 100 | 1 | |a Afshari, Khashayar |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effect of hybrid FES exercise on body composition during the sub-acute phase of spinal cord injury |
| 264 | 1 | |c 2022 | |
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| 500 | |a Date Completed 21.02.2022 | ||
| 500 | |a Date Revised 21.02.2022 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVES: To determine the Effect of Hybrid functional electrically stimulated (FES) Exercise on Body Composition during the Sub-acute Phase of Spinal Cord Injury (SCI) | ||
| 520 | |a DESIGN: Randomized Clinical Trial | ||
| 520 | |a SETTING: Rehabilitation Hospital | ||
| 520 | |a PARTICIPANTS: Patients within sub-acute phase (3-24 months) of SCI | ||
| 520 | |a INTERVENTIONS: We investigated if high-intensity exercise training via the addition of functional electrically stimulated (FES) leg muscles, provides sufficient stimulus to mitigate against body composition changes in the sub-acute phase after SCI | ||
| 520 | |a MAIN OUTCOME MEASURES: We explored potential effects of FES row training (FESRT) on body fat gain, lean mass loss, and cardiometabolic parameters and compared the effects of 6-month of FESRT (n = 18) to standard of care (SOC, n = 13). Those in SOC were crossed over to FESRT | ||
| 520 | |a RESULTS: FESRT resulted in greater exercise capacity and a tendency for lesser total body fat accumulation with a significant increase in total and leg lean mass (p<0.05). In addition pelvis and total bone mineral density declines were significantly less (p<0.05). Compared to SOC, FESRT did not lead to any significant difference in insulin sensitivity or serum lipids. However, HbA1C levels were significantly decreased in SOC participants who crossed over to 6-month FESRT | ||
| 520 | |a CONCLUSION: FESRT early after SCI provides a sufficient stimulus to mitigate against detrimental body composition changes. This may lead to prevention of losses in lean mass, including bone | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 700 | 1 | |a Ozturk, Erin D |e verfasserin |4 aut | |
| 700 | 1 | |a Yates, Brandon |e verfasserin |4 aut | |
| 700 | 1 | |a Picard, Glen |e verfasserin |4 aut | |
| 700 | 1 | |a Taylor, J Andrew |e verfasserin |4 aut | |
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