Right Ventricular Pump Efficiency in Secundum-Type Atrial Septal Defect

BACKGROUND: A well-functioning cardiopulmonary system, which works as a pump, should generate adequate stroke volume with as little stroke work as possible. We propose a new composite parameter, right ventricular (RV) pump efficiency (η) = left ventricular stroke volume / right ventricular stroke work, to describe this idea in a volume overload population with secundum-type atrial septal defect (ASD).

METHODS: We consecutively enrolled 50 patients with secundum-type ASD to investigate the relationship between right-sided volume overload and RV pump efficiency. Sixteen patients with a pulmonary to systemic flow ratio (Qp/Qs) > 1.5 underwent implantation of an occluder. The paired t test was used to compare RV pump efficiency before and after ASD closure.

RESULTS: RV pump efficiency was inversely correlated with Qp/Qs and was 60 ± 20‰ · mmHg-1 at Qp/Qs = 1. After ASD closure, RV volume, ejection fraction and free wall strain all significantly decreased, while RV pump efficiency significantly increased from 27.4 ± 13.6 to 63.9 ± 20.4‰ · mmHg-1.

CONCLUSIONS: RV pump efficiency can superiorly reflect the chronicity and severity of secundum-type ASD.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:38

Enthalten in:

Acta Cardiologica Sinica - 38(2022), 1 vom: 28. Jan., Seite 47-55

Sprache:

Englisch

Beteiligte Personen:

Lai, Wei-Tsung [VerfasserIn]
Yu, Ho-Ping [VerfasserIn]
Lin, Chang-Chyi [VerfasserIn]
Yin, Wei-Hsian [VerfasserIn]
Ko, Tsung-Yu [VerfasserIn]
Hwang, Juey-Jen [VerfasserIn]
Lin, Lung-Chun [VerfasserIn]
Huang, Kuan-Chih [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Right ventricular pump efficiency
Three-dimensional echocardiography
Volumetric analysis

Anmerkungen:

Date Revised 30.04.2022

published: Print

Citation Status PubMed-not-MEDLINE

doi:

10.6515/ACS.202201_38(1).20210721A

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM336034369