SARS-CoV-2 Saliva Mass Screening in Primary Schools : A 10-Week Sentinel Surveillance Study in Munich, Germany

Representative, actively collected surveillance data on asymptomatic SARS-CoV-2 infections in primary schoolchildren remain scarce. We evaluated the feasibility of a saliva mass screening concept and assessed infectious activity in primary schools. During a 10-week period from 3 March to 21 May 2021, schoolchildren and staff from 17 primary schools in Munich participated in the sentinel surveillance, cohort study. Participants were tested using the Salivette® system, testing was supervised by trained school staff, and samples were processed via reverse transcription quantitative polymerase chain reaction (RT-qPCR). We included 4433 participants: 3752 children (median age, 8 [range, 6-13] years; 1926 girls [51%]) and 681 staff members (median age, 41 [range, 14-71] years; 592 women [87%]). In total, 23,905 samples were processed (4640 from staff), with participants representing 8.3% of all primary schoolchildren in Munich. Only eight cases were detected: Five out of 3752 participating children (0.13%) and three out of 681 staff members (0.44%). There were no secondary cases. In conclusion, supervised Salivette® self-sampling was feasible, reliable, and safe and thus constituted an ideal method for SARS-CoV-2 mass screenings in primary schoolchildren. Our findings suggest that infectious activity among asymptomatic primary schoolchildren and staff was low. Primary schools appear to continue to play a minor role in the spread of SARS-CoV-2 despite high community incidence rates.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:12

Enthalten in:

Diagnostics (Basel, Switzerland) - 12(2022), 1 vom: 11. Jan.

Sprache:

Englisch

Beteiligte Personen:

Vogel, Sebastian [VerfasserIn]
von Both, Ulrich [VerfasserIn]
Nowak, Elisabeth [VerfasserIn]
Ludwig, Janina [VerfasserIn]
Köhler, Alexandra [VerfasserIn]
Lee, Noah [VerfasserIn]
Dick, Elisabeth [VerfasserIn]
Rack-Hoch, Anita [VerfasserIn]
Wicklein, Bernd [VerfasserIn]
Neusser, Jessica [VerfasserIn]
Wagner, Tobias [VerfasserIn]
Schubö, Alexandra [VerfasserIn]
Ustinov, Maxim [VerfasserIn]
Schimana, Werner [VerfasserIn]
Busche, Stephan [VerfasserIn]
Kolberg, Laura [VerfasserIn]
Hoch, Martin [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Mass screening
Primary school
RT-qPCR
SARS-CoV-2
Saliva
Salivette®

Anmerkungen:

Date Revised 05.04.2024

published: Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.3390/diagnostics12010162

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM335889719