Schizophrenia and Hospital Admissions for Cardiovascular Events in a Large Population : The APNA Study

(1) Background: Patients with schizophrenia have higher mortality, with cardiovascular diseases being the first cause of mortality. This study aims to estimate the excess risk of hospital admission for cardiovascular events in schizophrenic patients, adjusting for comorbidity and risk factors. (2) Methods: The APNA study is a dynamic prospective cohort of all residents in Navarra, Spain. A total of 505,889 people over 18 years old were followed for five years. The endpoint was hospital admissions for a cardiovascular event. Direct Acyclic Graphs (DAG) and Cox regression were used. (3) Results: Schizophrenic patients had a Hazard Ratio (HR) of 1.414 (95% CI 1.031-1.938) of hospital admission for a cardiovascular event after adjusting for age, sex, hypertension, type 2 diabetes, dyslipidemia, smoking, low income, obesity, antecedents of cardiovascular disease, and smoking. In non-adherent to antipsychotic treatment schizophrenia patients, the HR was 2.232 (95% CI 1.267-3.933). (4) Conclusions: Patients with schizophrenia have a higher risk of hospital admission for cardiovascular events than persons with the same risk factors without schizophrenia. Primary care nursing interventions should monitor these patients and reduce cardiovascular risk factors.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:9

Enthalten in:

Journal of cardiovascular development and disease - 9(2022), 1 vom: 13. Jan.

Sprache:

Englisch

Beteiligte Personen:

Guillen-Aguinaga, Sara [VerfasserIn]
Brugos-Larumbe, Antonio [VerfasserIn]
Guillen-Aguinaga, Laura [VerfasserIn]
Ortuño, Felipe [VerfasserIn]
Guillen-Grima, Francisco [VerfasserIn]
Forga, Luis [VerfasserIn]
Aguinaga-Ontoso, Ines [VerfasserIn]

Links:

Volltext

Themen:

Cardiovascular
Hospital admissions
Journal Article
Prospective cohort
Schizophrenia

Anmerkungen:

Date Revised 23.01.2022

published: Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.3390/jcdd9010025

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM335848915