Association between air pollution exposure and mental health service use among individuals with first presentations of psychotic and mood disorders : retrospective cohort study
BACKGROUND: Growing evidence suggests that air pollution exposure may adversely affect the brain and increase risk for psychiatric disorders such as schizophrenia and depression. However, little is known about the potential role of air pollution in severity and relapse following illness onset.
AIMS: To examine the longitudinal association between residential air pollution exposure and mental health service use (an indicator of illness severity and relapse) among individuals with first presentations of psychotic and mood disorders.
METHOD: We identified individuals aged ≥15 years who had first contact with the South London and Maudsley NHS Foundation Trust for psychotic and mood disorders in 2008-2012 (n = 13 887). High-resolution (20 × 20 m) estimates of nitrogen dioxide (NO2), nitrogen oxides (NOx) and particulate matter (PM2.5 and PM10) levels in ambient air were linked to residential addresses. In-patient days and community mental health service (CMHS) events were recorded over 1-year and 7-year follow-up periods.
RESULTS: Following covariate adjustment, interquartile range increases in NO2, NOx and PM2.5 were associated with 18% (95% CI 5-34%), 18% (95% CI 5-34%) and 11% (95% CI 3-19%) increased risk for in-patient days after 1 year. Similarly, interquartile range increases in NO2, NOx, PM2.5 and PM10 were associated with 32% (95% CI 25-38%), 31% (95% CI 24-37%), 7% (95% CI 4-11%) and 9% (95% CI 5-14%) increased risk for CMHS events after 1 year. Associations persisted after 7 years.
CONCLUSIONS: Residential air pollution exposure is associated with increased mental health service use among people recently diagnosed with psychotic and mood disorders. Assuming causality, interventions to reduce air pollution exposure could improve mental health prognoses and reduce healthcare costs.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:219 |
|---|---|
| Enthalten in: |
The British journal of psychiatry : the journal of mental science - 219(2021), 6 vom: 20. Dez., Seite 678-685 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Newbury, Joanne B [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Air Pollutants |
|---|
| Anmerkungen: |
Date Completed 13.04.2022 Date Revised 13.04.2022 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1192/bjp.2021.119 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM335835295 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM335835295 | ||
| 003 | DE-627 | ||
| 005 | 20231225230749.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1192/bjp.2021.119 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1119.xml |
| 035 | |a (DE-627)NLM335835295 | ||
| 035 | |a (NLM)35048872 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Newbury, Joanne B |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Association between air pollution exposure and mental health service use among individuals with first presentations of psychotic and mood disorders |b retrospective cohort study |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 13.04.2022 | ||
| 500 | |a Date Revised 13.04.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Growing evidence suggests that air pollution exposure may adversely affect the brain and increase risk for psychiatric disorders such as schizophrenia and depression. However, little is known about the potential role of air pollution in severity and relapse following illness onset | ||
| 520 | |a AIMS: To examine the longitudinal association between residential air pollution exposure and mental health service use (an indicator of illness severity and relapse) among individuals with first presentations of psychotic and mood disorders | ||
| 520 | |a METHOD: We identified individuals aged ≥15 years who had first contact with the South London and Maudsley NHS Foundation Trust for psychotic and mood disorders in 2008-2012 (n = 13 887). High-resolution (20 × 20 m) estimates of nitrogen dioxide (NO2), nitrogen oxides (NOx) and particulate matter (PM2.5 and PM10) levels in ambient air were linked to residential addresses. In-patient days and community mental health service (CMHS) events were recorded over 1-year and 7-year follow-up periods | ||
| 520 | |a RESULTS: Following covariate adjustment, interquartile range increases in NO2, NOx and PM2.5 were associated with 18% (95% CI 5-34%), 18% (95% CI 5-34%) and 11% (95% CI 3-19%) increased risk for in-patient days after 1 year. Similarly, interquartile range increases in NO2, NOx, PM2.5 and PM10 were associated with 32% (95% CI 25-38%), 31% (95% CI 24-37%), 7% (95% CI 4-11%) and 9% (95% CI 5-14%) increased risk for CMHS events after 1 year. Associations persisted after 7 years | ||
| 520 | |a CONCLUSIONS: Residential air pollution exposure is associated with increased mental health service use among people recently diagnosed with psychotic and mood disorders. Assuming causality, interventions to reduce air pollution exposure could improve mental health prognoses and reduce healthcare costs | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Air pollution | |
| 650 | 4 | |a cohort study | |
| 650 | 4 | |a illness severity and relapse | |
| 650 | 4 | |a mood disorders | |
| 650 | 4 | |a psychotic disorders | |
| 650 | 7 | |a Air Pollutants |2 NLM | |
| 650 | 7 | |a Particulate Matter |2 NLM | |
| 650 | 7 | |a Nitrogen Dioxide |2 NLM | |
| 650 | 7 | |a S7G510RUBH |2 NLM | |
| 700 | 1 | |a Stewart, Robert |e verfasserin |4 aut | |
| 700 | 1 | |a Fisher, Helen L |e verfasserin |4 aut | |
| 700 | 1 | |a Beevers, Sean |e verfasserin |4 aut | |
| 700 | 1 | |a Dajnak, David |e verfasserin |4 aut | |
| 700 | 1 | |a Broadbent, Matthew |e verfasserin |4 aut | |
| 700 | 1 | |a Pritchard, Megan |e verfasserin |4 aut | |
| 700 | 1 | |a Shiode, Narushige |e verfasserin |4 aut | |
| 700 | 1 | |a Heslin, Margaret |e verfasserin |4 aut | |
| 700 | 1 | |a Hammoud, Ryan |e verfasserin |4 aut | |
| 700 | 1 | |a Hotopf, Matthew |e verfasserin |4 aut | |
| 700 | 1 | |a Hatch, Stephani L |e verfasserin |4 aut | |
| 700 | 1 | |a Mudway, Ian S |e verfasserin |4 aut | |
| 700 | 1 | |a Bakolis, Ioannis |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The British journal of psychiatry : the journal of mental science |d 1963 |g 219(2021), 6 vom: 20. Dez., Seite 678-685 |w (DE-627)NLM000014893 |x 1472-1465 |7 nnns |
| 773 | 1 | 8 | |g volume:219 |g year:2021 |g number:6 |g day:20 |g month:12 |g pages:678-685 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1192/bjp.2021.119 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 219 |j 2021 |e 6 |b 20 |c 12 |h 678-685 | ||