Immunogenicity of Nickel-Further Explored

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Recent reports of the relationship between nickel, allergy and autoimmunity have been described. However, there remains a lack of information on the concordance between nickel sensitization and potency. Of note, an article by Drenovska et al. recommended a call for increased epidemiologic studies to define the prevalence of autoimmune syndromes induced by adjuvants such as nickel-containing metal implants. Accumulating reports of dermatologic manifestations following medical device implantation highlights the need for consideration regarding the potential sequelae following metal implantation. Considering the medical and the functional necessity of certain device materials, the authors agree calling for further epidemiological studies are needed to prevent metal-related autoimmunity, and additionally discover novel testing strategies.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:21

Enthalten in:

Endocrine, metabolic & immune disorders drug targets - 21(2021), 12 vom: 14., Seite 2117-2118

Sprache:

Englisch

Beteiligte Personen:

Baghchechi, Mohsen [VerfasserIn]
Jacob, Sharon E [VerfasserIn]

Links:

Volltext

Themen:

7OV03QG267
Allergy
Autoimmune
Epidemiology
Hypersensitivity
Immunology
Journal Article
Metal implant
Metals
Nickel

Anmerkungen:

Date Completed 04.04.2022

Date Revised 05.04.2022

published: Print

Citation Status MEDLINE

doi:

10.2174/1871530321666210310143600

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM335618413