Clinical feasibility of transfer to combined therapy with peritoneal dialysis and hemodialysis for patients on peritoneal dialysis : A prospective multicenter study in Japan
© 2022 International Society for Apheresis and Japanese Society for Apheresis..
INTRODUCTION: Although combined therapy with peritoneal dialysis (PD) and hemodialysis (HD) is widespread in Japan, its clinical utility has been reported only in retrospective or before-and-after test lacking a control group.
METHODS: We conducted a prospective, multicenter, observational cohort study of 176 incident PD patients and compared patient survival and changes in clinical parameters between patients on different dialysis modalities.
RESULTS: During a median follow-up of 41 months, 47 patients transferred to combined therapy and 35 patients transferred directly to HD. Patients transferred to combined therapy had a significantly better survival than those transferred directly to HD. However, we could not establish this difference in a multivariate analysis because only six patients died among these groups. The decreases in urea nitrogen and serum creatinine were more prominent among patients directly transferred to HD.
CONCLUSION: This is the first report revealing clinical feasibility of transfer to combined therapy for PD patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
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| Enthalten in: |
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy - 26(2022), 6 vom: 15. Dez., Seite 1226-1234 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Maruyama, Yukio [VerfasserIn] |
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| Links: |
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| Themen: |
β2 microglobulin |
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| Anmerkungen: |
Date Completed 15.11.2022 Date Revised 15.11.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/1744-9987.13796 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM335355544 |
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| 100 | 1 | |a Maruyama, Yukio |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical feasibility of transfer to combined therapy with peritoneal dialysis and hemodialysis for patients on peritoneal dialysis |b A prospective multicenter study in Japan |
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| 500 | |a Date Revised 15.11.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2022 International Society for Apheresis and Japanese Society for Apheresis. | ||
| 520 | |a INTRODUCTION: Although combined therapy with peritoneal dialysis (PD) and hemodialysis (HD) is widespread in Japan, its clinical utility has been reported only in retrospective or before-and-after test lacking a control group | ||
| 520 | |a METHODS: We conducted a prospective, multicenter, observational cohort study of 176 incident PD patients and compared patient survival and changes in clinical parameters between patients on different dialysis modalities | ||
| 520 | |a RESULTS: During a median follow-up of 41 months, 47 patients transferred to combined therapy and 35 patients transferred directly to HD. Patients transferred to combined therapy had a significantly better survival than those transferred directly to HD. However, we could not establish this difference in a multivariate analysis because only six patients died among these groups. The decreases in urea nitrogen and serum creatinine were more prominent among patients directly transferred to HD | ||
| 520 | |a CONCLUSION: This is the first report revealing clinical feasibility of transfer to combined therapy for PD patients | ||
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a dialysate-to-plasma ratio of creatinine (D/P Cr) | |
| 650 | 4 | |a fluid overload | |
| 650 | 4 | |a inadequate dialysis | |
| 650 | 4 | |a residual renal function (RRF) | |
| 650 | 4 | |a β2 microglobulin | |
| 700 | 1 | |a Yokoyama, Keitaro |e verfasserin |4 aut | |
| 700 | 1 | |a Higuchi, Chieko |e verfasserin |4 aut | |
| 700 | 1 | |a Sanaka, Tsutomu |e verfasserin |4 aut | |
| 700 | 1 | |a Tanaka, Yoshihide |e verfasserin |4 aut | |
| 700 | 1 | |a Sakai, Ken |e verfasserin |4 aut | |
| 700 | 1 | |a Kanno, Yoshihiko |e verfasserin |4 aut | |
| 700 | 1 | |a Ryuzaki, Munekazu |e verfasserin |4 aut | |
| 700 | 1 | |a Sakurada, Tsutomu |e verfasserin |4 aut | |
| 700 | 1 | |a Hosoya, Tatsuo |e verfasserin |4 aut | |
| 700 | 1 | |a Nakayama, Masaaki |e verfasserin |4 aut | |
| 700 | 0 | |a EARTH (Evaluation of the Adequacy of Renal replacement THerapy) study group |e verfasserin |4 aut | |
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