Mid-term clinical and haemodynamic results after aortic valve replacement with the Trifecta bioprosthesis
© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved..
OBJECTIVES: The aim of this study was to evaluate the clinical and haemodynamic results after implantation of the Trifecta bioprosthesis.
METHODS: This study is a retrospective analysis of all patients undergoing Trifecta aortic valve replacement between 01 January 2012 and 31 December 2017 at the Ghent University Hospital. Univariable and multivariable analyses were performed to identify predictors of valve- and procedure-related complications and mortality. The haemodynamic performance was analysed by longitudinal Doppler echocardiography.
RESULTS: The mean age of the 182 patients was 77 [standard deviation (SD): 5.5] years; 54.9% were women. The mean follow-up was 39.8 (SD: 24.3) months. Overall survival at 1 and 5 years was 86% (SD: 3%) and 68% (SD: 4%), respectively, and overall freedom from structural valve deterioration was 100% and 98% at 1 and 5 years, respectively. There was no valve thrombosis nor early endocarditis. Urgent surgery was the only risk factor for early mortality in the multivariable analysis [P = 0.009, odds ratio 0.06, 95% confidence interval (CI) 0.01-0.5]. Preoperative atrial fibrillation was the most important predictor of late mortality (P = 0.001, hazard ratio 3.68, 95% CI 1.65-8.21). The average peak gradients were stable from discharge up to 1 and 5 years postoperatively [15 (SD: 6) and 17 (SD: 8) mmHg].
CONCLUSIONS: These results confirm the excellent clinical performance of the Trifecta valve, particularly in an elderly age group. Through the 7-year follow-up period, low transvalvular gradients persisted, and only a few patients needed reoperation. Although structural valve degeneration occurred rarely, it was unrelated to valve size or age at implantation; therefore, further long-term follow-up remains mandatory.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:34 |
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| Enthalten in: |
Interactive cardiovascular and thoracic surgery - 34(2022), 1 vom: 06. Jan., Seite 16-25 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Mortelé, Augustijn [VerfasserIn] |
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| Links: |
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| Themen: |
Aortic valve stenosis |
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| Anmerkungen: |
Date Completed 07.03.2022 Date Revised 19.10.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1093/icvts/ivab205 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM335350909 |
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| 245 | 1 | 0 | |a Mid-term clinical and haemodynamic results after aortic valve replacement with the Trifecta bioprosthesis |
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| 500 | |a Date Revised 19.10.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved. | ||
| 520 | |a OBJECTIVES: The aim of this study was to evaluate the clinical and haemodynamic results after implantation of the Trifecta bioprosthesis | ||
| 520 | |a METHODS: This study is a retrospective analysis of all patients undergoing Trifecta aortic valve replacement between 01 January 2012 and 31 December 2017 at the Ghent University Hospital. Univariable and multivariable analyses were performed to identify predictors of valve- and procedure-related complications and mortality. The haemodynamic performance was analysed by longitudinal Doppler echocardiography | ||
| 520 | |a RESULTS: The mean age of the 182 patients was 77 [standard deviation (SD): 5.5] years; 54.9% were women. The mean follow-up was 39.8 (SD: 24.3) months. Overall survival at 1 and 5 years was 86% (SD: 3%) and 68% (SD: 4%), respectively, and overall freedom from structural valve deterioration was 100% and 98% at 1 and 5 years, respectively. There was no valve thrombosis nor early endocarditis. Urgent surgery was the only risk factor for early mortality in the multivariable analysis [P = 0.009, odds ratio 0.06, 95% confidence interval (CI) 0.01-0.5]. Preoperative atrial fibrillation was the most important predictor of late mortality (P = 0.001, hazard ratio 3.68, 95% CI 1.65-8.21). The average peak gradients were stable from discharge up to 1 and 5 years postoperatively [15 (SD: 6) and 17 (SD: 8) mmHg] | ||
| 520 | |a CONCLUSIONS: These results confirm the excellent clinical performance of the Trifecta valve, particularly in an elderly age group. Through the 7-year follow-up period, low transvalvular gradients persisted, and only a few patients needed reoperation. Although structural valve degeneration occurred rarely, it was unrelated to valve size or age at implantation; therefore, further long-term follow-up remains mandatory | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Aortic valve stenosis | |
| 650 | 4 | |a Bioprosthesis | |
| 650 | 4 | |a Postoperative complications/epidemiology | |
| 650 | 4 | |a Survival rate | |
| 650 | 4 | |a Treatment outcome | |
| 700 | 1 | |a Dereu, Alexander |e verfasserin |4 aut | |
| 700 | 1 | |a Bové, Thierry |e verfasserin |4 aut | |
| 700 | 1 | |a François, Katrien |e verfasserin |4 aut | |
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