Response to Hydroxyurea in a Patient With Sickle Cell Hepatopathy : A Case Report

Copyright © 2021, Safhi et al..

Sickle cell hepatopathy is an underreported entity lacking clear management guidelines. This case highlights the potential role of hydroxyurea (HU) in improving the hepatic dysfunction seen among patients with sickle cell disease (SCD). We herein present the clinical course of a patient prior to and after the initiation of hydroxyurea with an emphasis on long-term outcomes and the patterns of liver injury over a 15-year time course.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

Cureus - 13(2021), 12 vom: 27. Dez., Seite e20649

Sprache:

Englisch

Beteiligte Personen:

Safhi, Maha A [VerfasserIn]
Baghdadi, Rana M [VerfasserIn]
Al-Marzouki, Adel F [VerfasserIn]
Al-Sayes, Fatin [VerfasserIn]

Links:

Volltext

Themen:

Case Reports
Exchange blood transfusions
Hydroxyurea
Sickle cell disease
Sickle cell intrahepatic cholestasis
Sickle hepatopathy

Anmerkungen:

Date Revised 04.01.2022

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.7759/cureus.20649

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM335120261