Liposomes for the Delivery of Lipopeptide Vaccines
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature..
Liposomes, which are artificial phospholipid vesicles with a bilayer membrane structure, have been developed and evaluated as a promising delivery system for vaccines. Here, we describe a procedure for the encapsulation of lipopeptide vaccines into liposomes. A liposomal formulation of lipid-core peptide was prepared via thin-film hydration followed by extrusion. The physicochemical properties of the liposomes, including their size, polydispersity, surface charge, and morphology, were analyzed using dynamic light scattering and transmission electron microscopy.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2022 |
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Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:2412 |
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Enthalten in: |
Methods in molecular biology (Clifton, N.J.) - 2412(2022) vom: 17., Seite 295-307 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Yang, Jieru [VerfasserIn] |
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Links: |
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Themen: |
Extrusion |
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Anmerkungen: |
Date Completed 20.01.2022 Date Revised 20.01.2022 published: Print Citation Status MEDLINE |
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doi: |
10.1007/978-1-0716-1892-9_15 |
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funding: |
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Förderinstitution / Projekttitel: |
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520 | |a Liposomes, which are artificial phospholipid vesicles with a bilayer membrane structure, have been developed and evaluated as a promising delivery system for vaccines. Here, we describe a procedure for the encapsulation of lipopeptide vaccines into liposomes. A liposomal formulation of lipid-core peptide was prepared via thin-film hydration followed by extrusion. The physicochemical properties of the liposomes, including their size, polydispersity, surface charge, and morphology, were analyzed using dynamic light scattering and transmission electron microscopy | ||
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