Liposomes for the Delivery of Lipopeptide Vaccines

© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature..

Liposomes, which are artificial phospholipid vesicles with a bilayer membrane structure, have been developed and evaluated as a promising delivery system for vaccines. Here, we describe a procedure for the encapsulation of lipopeptide vaccines into liposomes. A liposomal formulation of lipid-core peptide was prepared via thin-film hydration followed by extrusion. The physicochemical properties of the liposomes, including their size, polydispersity, surface charge, and morphology, were analyzed using dynamic light scattering and transmission electron microscopy.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:2412

Enthalten in:

Methods in molecular biology (Clifton, N.J.) - 2412(2022) vom: 17., Seite 295-307

Sprache:

Englisch

Beteiligte Personen:

Yang, Jieru [VerfasserIn]
Azuar, Armira [VerfasserIn]
Toth, Istvan [VerfasserIn]
Skwarczynski, Mariusz [VerfasserIn]

Links:

Volltext

Themen:

Extrusion
Journal Article
Lipopeptides
Liposomes
Phospholipids
Vaccine delivery
Vaccines

Anmerkungen:

Date Completed 20.01.2022

Date Revised 20.01.2022

published: Print

Citation Status MEDLINE

doi:

10.1007/978-1-0716-1892-9_15

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM334544394