Rapidly Progressive Granulomatous Amoebic Encephalitis in a Diabetic Individual
Copyright © 2021, Paudel et al..
We present a case of rapidly progressive granulomatous amoebic encephalitis caused by Balamuthia mandrillaris in an individual with diabetes mellitus. Our patient presented with occipital headache, blurry vision, confusion, and gait imbalance of one week's duration. Brain imaging revealed numerous peripheral ring-enhancing lesions concerning malignancy. Brain biopsy was consistent with Balamuthia mandrillaris infection. He passed away 45 days after presentation despite being treated with a five-drug regimen. This case highlights the importance of considering amoebic brain infections, especially with ring-enhancing lesions on imaging. There are opportunities to design modalities for rapid diagnosis and better treatment.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
Cureus - 13(2021), 11 vom: 24. Nov., Seite e19336 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Paudel, Anish C [VerfasserIn] |
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| Links: |
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| Themen: |
Amoebic encephalitis |
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| Anmerkungen: |
Date Revised 17.12.2021 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.7759/cureus.19336 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM334455626 |
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| 520 | |a Copyright © 2021, Paudel et al. | ||
| 520 | |a We present a case of rapidly progressive granulomatous amoebic encephalitis caused by Balamuthia mandrillaris in an individual with diabetes mellitus. Our patient presented with occipital headache, blurry vision, confusion, and gait imbalance of one week's duration. Brain imaging revealed numerous peripheral ring-enhancing lesions concerning malignancy. Brain biopsy was consistent with Balamuthia mandrillaris infection. He passed away 45 days after presentation despite being treated with a five-drug regimen. This case highlights the importance of considering amoebic brain infections, especially with ring-enhancing lesions on imaging. There are opportunities to design modalities for rapid diagnosis and better treatment | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a amoebic encephalitis | |
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| 700 | 1 | |a Sigal, Adam |e verfasserin |4 aut | |
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| 700 | 1 | |a Oladunjoye, Olubunmi |e verfasserin |4 aut | |
| 700 | 1 | |a Oke, Ibiyemi O |e verfasserin |4 aut | |
| 700 | 1 | |a Khanal, Suravi |e verfasserin |4 aut | |
| 700 | 1 | |a Bhattarai, Kristina |e verfasserin |4 aut | |
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