Fibrinogen-to-albumin ratio predicts mortality in COVID-19 patients admitted to the intensive care unit
INTRODUCTION: Coronavirus disease 2019 (COVID-19) is an inflammatory disease, and serum albumin and fibrinogen are two important factors in systemic inflammation. We aimed to investigate the relationship between the fibrinogen-to-albumin ratio (FAR) and in-hospital mortality in COVID-19 patients admitted to the intensive care unit (ICU).
MATERIAL AND METHODS: Patients diagnosed with COVID-19 admitted to the Adiyaman Training and Research Hospital from August to November 2020 were enrolled in this retrospective cohort study. They were divided into 2 groups based on in-hospital mortality: a survivor group (n = 188) and a non-survivor group (n = 198). FAR was calculated by dividing the fibrinogen value by the albumin value. Mortality outcomes were followed up until December 15, 2020.
RESULTS: The average age of the patients was 71.2 ± 12.9 years, and 54% were male. On multivariate logistic analysis, diabetes mellitus (OR: 1.806; 95% CI: 1.142-2.856; p = 0.011), troponin I levels (OR: 1.776; 95% CI: 1.031-3.061; p = 0.038), and FAR (OR: 1.004; 95% CI: 1.004-1.007; p = 0.010) at ICU admission were independent predictors of in-hospital mortality in patients with COVID-19.
CONCLUSIONS: The FAR at admission was associated with mortality in patients infected with SARS-CoV-2 in the ICU.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2021 |
|---|---|
| Enthalten in: |
Advances in respiratory medicine - (2021) vom: 09. Dez. |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Afşin, Abdulmecit [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Coronavirus disease 2019 |
|---|
| Anmerkungen: |
Date Revised 20.02.2024 published: Print-Electronic Citation Status Publisher |
|---|
| doi: |
10.5603/ARM.a2021.0098 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM334183707 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM334183707 | ||
| 003 | DE-627 | ||
| 005 | 20240220231951.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.5603/ARM.a2021.0098 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1300.xml |
| 035 | |a (DE-627)NLM334183707 | ||
| 035 | |a (NLM)34881805 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Afşin, Abdulmecit |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Fibrinogen-to-albumin ratio predicts mortality in COVID-19 patients admitted to the intensive care unit |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 20.02.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status Publisher | ||
| 520 | |a INTRODUCTION: Coronavirus disease 2019 (COVID-19) is an inflammatory disease, and serum albumin and fibrinogen are two important factors in systemic inflammation. We aimed to investigate the relationship between the fibrinogen-to-albumin ratio (FAR) and in-hospital mortality in COVID-19 patients admitted to the intensive care unit (ICU) | ||
| 520 | |a MATERIAL AND METHODS: Patients diagnosed with COVID-19 admitted to the Adiyaman Training and Research Hospital from August to November 2020 were enrolled in this retrospective cohort study. They were divided into 2 groups based on in-hospital mortality: a survivor group (n = 188) and a non-survivor group (n = 198). FAR was calculated by dividing the fibrinogen value by the albumin value. Mortality outcomes were followed up until December 15, 2020 | ||
| 520 | |a RESULTS: The average age of the patients was 71.2 ± 12.9 years, and 54% were male. On multivariate logistic analysis, diabetes mellitus (OR: 1.806; 95% CI: 1.142-2.856; p = 0.011), troponin I levels (OR: 1.776; 95% CI: 1.031-3.061; p = 0.038), and FAR (OR: 1.004; 95% CI: 1.004-1.007; p = 0.010) at ICU admission were independent predictors of in-hospital mortality in patients with COVID-19 | ||
| 520 | |a CONCLUSIONS: The FAR at admission was associated with mortality in patients infected with SARS-CoV-2 in the ICU | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a coronavirus disease 2019 | |
| 650 | 4 | |a fibrinogen-to-albumin ratio | |
| 650 | 4 | |a intensive care unit | |
| 650 | 4 | |a mortality | |
| 700 | 1 | |a Tibilli, Hakan |e verfasserin |4 aut | |
| 700 | 1 | |a Hoşoğlu, Yusuf |e verfasserin |4 aut | |
| 700 | 1 | |a Asoğlu, Ramazan |e verfasserin |4 aut | |
| 700 | 1 | |a Süsenbük, Ahmet |e verfasserin |4 aut | |
| 700 | 1 | |a Markirt, Sezer |e verfasserin |4 aut | |
| 700 | 1 | |a Tuna, Verda Dinar |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Advances in respiratory medicine |d 2016 |g (2021) vom: 09. Dez. |w (DE-627)NLM267415613 |x 2543-6031 |7 nnns |
| 773 | 1 | 8 | |g year:2021 |g day:09 |g month:12 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.5603/ARM.a2021.0098 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |j 2021 |b 09 |c 12 | ||