Assessing the relationship between ALT level with disease progression and treatment timing
Serum alanine aminotransferase (ALT) is a sensitive and important marker of liver injury, which is closely related to the disease progression. It is the key rather than the only parameter to initiate treatment decisions for patients with chronic hepatitis B virus infection. The normal reference range of ALT is derived from epidemiological investigation of healthy population, which varies among different countries, regions or laboratories. Hepatologists should conduct a large number of cohort clinical studies based on the natural history and the prognosis of the disease, and adjust the cut-off value of ALT levels to make clinical decisions in order to determine the degree of liver injury, the treatment initiation and response.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:28 |
|---|---|
| Enthalten in: |
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 28(2020), 12 vom: 20. Dez., Seite 992-994 |
| Sprache: |
Chinesisch |
|---|
| Beteiligte Personen: |
Liang, X E [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Alanine Transaminase |
|---|
| Anmerkungen: |
Date Completed 07.12.2021 Date Revised 14.12.2021 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.3760/cma.j.cn501113-20201022-00571 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM334020794 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM334020794 | ||
| 003 | DE-627 | ||
| 005 | 20231225222838.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2020 xx |||||o 00| ||chi c | ||
| 024 | 7 | |a 10.3760/cma.j.cn501113-20201022-00571 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1113.xml |
| 035 | |a (DE-627)NLM334020794 | ||
| 035 | |a (NLM)34865344 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a chi | ||
| 100 | 1 | |a Liang, X E |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Assessing the relationship between ALT level with disease progression and treatment timing |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 07.12.2021 | ||
| 500 | |a Date Revised 14.12.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Serum alanine aminotransferase (ALT) is a sensitive and important marker of liver injury, which is closely related to the disease progression. It is the key rather than the only parameter to initiate treatment decisions for patients with chronic hepatitis B virus infection. The normal reference range of ALT is derived from epidemiological investigation of healthy population, which varies among different countries, regions or laboratories. Hepatologists should conduct a large number of cohort clinical studies based on the natural history and the prognosis of the disease, and adjust the cut-off value of ALT levels to make clinical decisions in order to determine the degree of liver injury, the treatment initiation and response | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Alanine aminotransferase | |
| 650 | 4 | |a Antiviral treatment | |
| 650 | 4 | |a Disease progression | |
| 650 | 4 | |a Hepatitis B | |
| 650 | 4 | |a Normal range | |
| 650 | 7 | |a Alanine Transaminase |2 NLM | |
| 650 | 7 | |a EC 2.6.1.2 |2 NLM | |
| 700 | 1 | |a Sun, J |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology |d 1998 |g 28(2020), 12 vom: 20. Dez., Seite 992-994 |w (DE-627)NLM096493321 |x 1007-3418 |7 nnns |
| 773 | 1 | 8 | |g volume:28 |g year:2020 |g number:12 |g day:20 |g month:12 |g pages:992-994 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3760/cma.j.cn501113-20201022-00571 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 28 |j 2020 |e 12 |b 20 |c 12 |h 992-994 | ||