Neurotropism and Neuropsychiatric Symptomsi in Patients with COVID-19
BACKGROUND: The Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the Severe Acute Respiratory Syndrome-CoronaVirus-2 (SARS-CoV-2). Beyond the most common clinical features of COVID-19, mainly represented by respiratory symptoms, other systems may be interested by the infection. Among these, through a neurotropic pathway, the central nervous system (CNS) may be affected by the virus, leading to developing neuropsychiatric symptoms. Particularly, this study focuses on neurological symptoms determined by the Sars-CoV-2 infection, as well as on the underlying pathogenetic processes.
METHODS: For the present review, we followed a narrative approach. A literature search was carried out concerning the neurological consequences of COVID-19. Papers were screened, focusing on the clinical manifestations interesting the CNS and on their possible role in the early diagnosis of the disease.
RESULTS: We display the most significant neurological clinical manifestations of COVID-19. Common neurological manifestations (ageusia, anosmia, and encephalitis) are first described. Subsequently, we provide a focus on delirium and its possible pathogenetic and clinical correlates. Delirium is not only a possible resultant of the COVID-19 neurotropism, but it may also be precipitated by a number of environmental factors that assume further relevance during the pandemic.
CONCLUSIONS: Neuropsychiatric symptoms, and particularly delirium, can help identifying the infection at an early stage. Tailored treatments should be identified in order to prevent complications.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:33 |
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| Enthalten in: |
Psychiatria Danubina - 33(2021), Suppl 11 vom: 04. Dez., Seite 10-13 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Moretti, Patrizia [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 07.12.2021 Date Revised 14.12.2021 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM333996291 |
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| 245 | 1 | 0 | |a Neurotropism and Neuropsychiatric Symptomsi in Patients with COVID-19 |
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| 500 | |a Date Revised 14.12.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: The Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the Severe Acute Respiratory Syndrome-CoronaVirus-2 (SARS-CoV-2). Beyond the most common clinical features of COVID-19, mainly represented by respiratory symptoms, other systems may be interested by the infection. Among these, through a neurotropic pathway, the central nervous system (CNS) may be affected by the virus, leading to developing neuropsychiatric symptoms. Particularly, this study focuses on neurological symptoms determined by the Sars-CoV-2 infection, as well as on the underlying pathogenetic processes | ||
| 520 | |a METHODS: For the present review, we followed a narrative approach. A literature search was carried out concerning the neurological consequences of COVID-19. Papers were screened, focusing on the clinical manifestations interesting the CNS and on their possible role in the early diagnosis of the disease | ||
| 520 | |a RESULTS: We display the most significant neurological clinical manifestations of COVID-19. Common neurological manifestations (ageusia, anosmia, and encephalitis) are first described. Subsequently, we provide a focus on delirium and its possible pathogenetic and clinical correlates. Delirium is not only a possible resultant of the COVID-19 neurotropism, but it may also be precipitated by a number of environmental factors that assume further relevance during the pandemic | ||
| 520 | |a CONCLUSIONS: Neuropsychiatric symptoms, and particularly delirium, can help identifying the infection at an early stage. Tailored treatments should be identified in order to prevent complications | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 700 | 1 | |a Brufani, Francesca |e verfasserin |4 aut | |
| 700 | 1 | |a Pierotti, Valentina |e verfasserin |4 aut | |
| 700 | 1 | |a Pomili, Giorgio |e verfasserin |4 aut | |
| 700 | 1 | |a Di Buò, Agata |e verfasserin |4 aut | |
| 700 | 1 | |a Giulietti, Cecilia |e verfasserin |4 aut | |
| 700 | 1 | |a Masini, Filippo |e verfasserin |4 aut | |
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| 700 | 1 | |a Bachetti, Massimo Claudio |e verfasserin |4 aut | |
| 700 | 1 | |a Menculini, Giulia |e verfasserin |4 aut | |
| 700 | 1 | |a Tortorella, Alfonso |e verfasserin |4 aut | |
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