A novel near-infrared theranostic probe for accurate cancer chemotherapy in vivo by a dual activation strategy

A novel theranostic probe called CX-B-DF is constructed for precise chemotherapy guided by near-infrared (NIR) fluorescence imaging. Moreover, the theranostic probe shows high cytotoxicity to cancer cells under dual activation (H2O2 and TP), which causes the accuracy of drug release to be improved and the toxic side effects to be reduced.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:57

Enthalten in:

Chemical communications (Cambridge, England) - 57(2021), 100 vom: 16. Dez., Seite 13768-13771

Sprache:

Englisch

Beteiligte Personen:

Wang, Wen-Xin [VerfasserIn]
Jiang, Wen-Li [VerfasserIn]
Mao, Guo-Jiang [VerfasserIn]
Tan, Zhi-Ke [VerfasserIn]
Tan, Min [VerfasserIn]
Li, Chun-Yan [VerfasserIn]

Links:

Volltext

Themen:

039LU44I5M
Antineoplastic Agents
BBX060AN9V
Boronic Acids
Coumarins
Doxifluridine
EC 2.4.2.4
Floxuridine
Fluorescent Dyes
Hydrogen Peroxide
Journal Article
Thymidine Phosphorylase
V1JK16Y2JP

Anmerkungen:

Date Completed 10.01.2022

Date Revised 26.02.2024

published: Electronic

Citation Status MEDLINE

doi:

10.1039/d1cc05864a

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM333965949