Maternal COVID-19 Infection and Possible Associated Adverse Neurological Fetal Outcomes, Two Case Reports

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INTRODUCTION: The long-term effects of prenatal coronavirus disease 2019 (COVID-19) infection on the fetal brain are mostly unknown at this time; however, there is increasing evidence being published.

CASE REPORT: Two cases of severe ventriculomegaly, neurological dysfunction, and seizures were found in neonates with prenatal exposure to COVID-19 infection during the first and third trimesters of pregnancy.

CONCLUSION: Inflammation during the prenatal and neonatal periods may be associated with neurological disorders or injury. Despite the presumed lack of vertical transmission, post-COVID-19 syndrome and its associated inflammation may have an impact on the unborn fetus. Hyper-vigilance and dissemination of adverse findings are of significant importance as we navigate through this evolving pandemic and its effects.

KEY POINTS: · Prenatal exposure to COVID-19 may affect the fetal brain.. · There is a possibility of neonatal neurological sequelae from maternal COVID-19.. · Does maternal COVID-19 infection cause infantile seizures?.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:39

Enthalten in:

American journal of perinatology - 39(2022), 12 vom: 18. Sept., Seite 1292-1298

Sprache:

Englisch

Beteiligte Personen:

Archuleta, Charlotte [VerfasserIn]
Wade, Christine [VerfasserIn]
Micetic, Becky [VerfasserIn]
Tian, Ashley [VerfasserIn]
Mody, Kartik [VerfasserIn]

Links:

Volltext

Themen:

Case Reports
Journal Article

Anmerkungen:

Date Completed 08.09.2022

Date Revised 07.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1055/a-1704-1929

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM333514351