Germline (Hereditary) Risk
For germline (hereditary) risk, standards of care are based on emerging evidence-based practice. Cancer may affect any individual, but some people are at higher risk than others. The majority of cancer cases are sporadic, caused by DNA damage that may occur in one cell (not an egg or sperm) and accumulate over a lifetime. Hereditary predisposition to cancer is caused by pathogenic variants in certain genes passed from parent to offspring through the egg or sperm and referred to as germline. In hereditary cancer syndromes, higher incidence, earlier age at onset, and patterns of cancer may be seen within families.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
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| Enthalten in: |
Clinical journal of oncology nursing - 25(2021), 6 vom: 01. Dez., Seite 21-22 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Schmitt, Mary L [VerfasserIn] |
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| Links: |
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| Themen: |
Cancer |
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| Anmerkungen: |
Date Completed 04.04.2022 Date Revised 05.04.2022 published: Print Citation Status MEDLINE |
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| doi: |
10.1188/21.CJON.S2.21-22 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM333374584 |
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| 520 | |a For germline (hereditary) risk, standards of care are based on emerging evidence-based practice. Cancer may affect any individual, but some people are at higher risk than others. The majority of cancer cases are sporadic, caused by DNA damage that may occur in one cell (not an egg or sperm) and accumulate over a lifetime. Hereditary predisposition to cancer is caused by pathogenic variants in certain genes passed from parent to offspring through the egg or sperm and referred to as germline. In hereditary cancer syndromes, higher incidence, earlier age at onset, and patterns of cancer may be seen within families | ||
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