Amiodarone-induced musical hallucinations

© 2021 MEDPRESS..

Musical hallucinations (MHs), a kind of auditory hallucinations (AHs), are a rarely observed phenomenon of abnormal perception of sound in the absence of an external auditory source. MHs are characterized by perception of melodies, music, or songs. AHs/MHs can be associated with hypoacusis, psychiatric or neurological diseases, intoxication and adverse reactions of different medications (e.g., propranolol, amantadine, voriconazole).

A CASE REPORT: The authors present a case of a 77-year-old male with advanced heart failure, recurrent episodes of atrial fibrillations and moderate hypoacusis, who mistakenly overdosed oral amiodarone (6 pills 200 mg each daily within 3 days). After administration of 12 pills during 2 days, he started hearing music and songs not heard by others. One day later, when the number of ingested pills increased to 18, he decided to discontinue amiodarone and consulted a cardiologist; no signs of physical, ECG or laboratory deterioration were observed. MHs disappeared next day and returned only as a single episode when he tried to restart amiodarone at a dose of 1 pill daily 2 weeks later. Finally, following complete removal of the medication, he experienced no MHs whatsoever. Amiodarone is known to seldom cause neurological or mental complications; however, MHs after the drug have never been reported so far.

Medienart:

Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:49

Enthalten in:

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego - 49(2021), 293 vom: 22. Okt., Seite 361-363

Sprache:

Englisch

Beteiligte Personen:

Elikowski, Waldemar [VerfasserIn]
Małek-Elikowska, Małgorzata [VerfasserIn]
Fertała, Natalia [VerfasserIn]
Zawodna-Marszałek, Magdalena [VerfasserIn]

Themen:

Amiodarone
Amiodarone adverse reactions
Auditory hallucinations
Case Reports
Hypoacusis
Journal Article
Musical hallucinations
N3RQ532IUT

Anmerkungen:

Date Completed 23.11.2021

Date Revised 28.04.2022

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM333373650