Visceral adiposity indicators and cardiovascular risk in hemodialytic patients
OBJECTIVE: Cardiovascular diseases represent the main cause of death in chronic kidney disease (CKD). We aimed to evaluate the prevalence and association of the hypertriglyceridemia-waist phenotype (HWP) and visceral adiposity index (VAI) with cardiometabolic risk factors (CR) in patients with CKD on hemodialysis (HD).
METHODS: The study is based on a cross-sectional design with 265 HD patients in two cities in northeastern Brazil. The VAI was calculated considering the variables body mass index (BMI), waist circumference (WC), triglycerides (TG) and high density lipoprotein cholesterol (HDL-c). HWP was defined as the concomitant elevation of WC and TG. The Poisson Regression Model with robust variance estimation was adjusted considering a hierarchical approach for explanatory variables. Prevalence ratios (PR) were also estimated. The level of significance adopted was 5%.
RESULTS: In our study HWP and VAI prevalence's were 29.82% and 58.49%, respectively. In the final model, there was an association between VAI and female gender (PR = 1.46; p < 0.0001) and high body fat (% BF) (PR = 1.33; p < 0.0019). HWP was associated with females (PR = 1.80; p = 0.002), alcohol consumption (PR = 1.58; p = 0.033), obesity (PR = 1.89; p = 0.0001), high %BF (PR = 1.76; p = 0.012) and reduced HDL-c (PR = 1.48; p = 0.035).
CONCLUSION: The HWP stood out as the association with more CR factors, representing a promising method for tracking cardiometabolic risk in HD patients, mainly female.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:65 |
|---|---|
| Enthalten in: |
Archives of endocrinology and metabolism - 65(2021), 6 vom: 24. Nov., Seite 811-820 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
de Almeida Melo, Dejane [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Adiposity |
|---|
| Anmerkungen: |
Date Completed 18.01.2022 Date Revised 03.04.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.20945/2359-3997000000421 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM333006925 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM333006925 | ||
| 003 | DE-627 | ||
| 005 | 20231225220736.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.20945/2359-3997000000421 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1109.xml |
| 035 | |a (DE-627)NLM333006925 | ||
| 035 | |a (NLM)34762791 | ||
| 035 | |a (PII)2359-3997000000421 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a de Almeida Melo, Dejane |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Visceral adiposity indicators and cardiovascular risk in hemodialytic patients |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 18.01.2022 | ||
| 500 | |a Date Revised 03.04.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: Cardiovascular diseases represent the main cause of death in chronic kidney disease (CKD). We aimed to evaluate the prevalence and association of the hypertriglyceridemia-waist phenotype (HWP) and visceral adiposity index (VAI) with cardiometabolic risk factors (CR) in patients with CKD on hemodialysis (HD) | ||
| 520 | |a METHODS: The study is based on a cross-sectional design with 265 HD patients in two cities in northeastern Brazil. The VAI was calculated considering the variables body mass index (BMI), waist circumference (WC), triglycerides (TG) and high density lipoprotein cholesterol (HDL-c). HWP was defined as the concomitant elevation of WC and TG. The Poisson Regression Model with robust variance estimation was adjusted considering a hierarchical approach for explanatory variables. Prevalence ratios (PR) were also estimated. The level of significance adopted was 5% | ||
| 520 | |a RESULTS: In our study HWP and VAI prevalence's were 29.82% and 58.49%, respectively. In the final model, there was an association between VAI and female gender (PR = 1.46; p < 0.0001) and high body fat (% BF) (PR = 1.33; p < 0.0019). HWP was associated with females (PR = 1.80; p = 0.002), alcohol consumption (PR = 1.58; p = 0.033), obesity (PR = 1.89; p = 0.0001), high %BF (PR = 1.76; p = 0.012) and reduced HDL-c (PR = 1.48; p = 0.035) | ||
| 520 | |a CONCLUSION: The HWP stood out as the association with more CR factors, representing a promising method for tracking cardiometabolic risk in HD patients, mainly female | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Chronic renal insufficiency | |
| 650 | 4 | |a adiposity | |
| 650 | 4 | |a cardiovascular diseases | |
| 650 | 7 | |a Triglycerides |2 NLM | |
| 700 | 1 | |a Dos Santos, Alcione Miranda |e verfasserin |4 aut | |
| 700 | 1 | |a Furtado, Elane Viana Hortegal |e verfasserin |4 aut | |
| 700 | 1 | |a França, Ana Karina Teixeira |e verfasserin |4 aut | |
| 700 | 1 | |a Dos Santos, Elisângela Milhomem |e verfasserin |4 aut | |
| 700 | 1 | |a de Arruda, Ilma Kruze Grande |e verfasserin |4 aut | |
| 700 | 1 | |a de Carvalho, Tuane Rodrigues |e verfasserin |4 aut | |
| 700 | 1 | |a Pinho, Claudia Porto Sabino |e verfasserin |4 aut | |
| 700 | 1 | |a da Silva Diniz, Alcides |e verfasserin |4 aut | |
| 700 | 1 | |a da Conceição Chaves de Lemos, Maria |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Archives of endocrinology and metabolism |d 2015 |g 65(2021), 6 vom: 24. Nov., Seite 811-820 |w (DE-627)NLM248552902 |x 2359-4292 |7 nnns |
| 773 | 1 | 8 | |g volume:65 |g year:2021 |g number:6 |g day:24 |g month:11 |g pages:811-820 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.20945/2359-3997000000421 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 65 |j 2021 |e 6 |b 24 |c 11 |h 811-820 | ||