Severe aplastic anemia exhibiting mild COVID-19 despite high serum IL-6 levels
COVID-19 is a viral infection characterized by a cytokine storm similar to that in acute respiratory distress syndrome (ARDS). Neutrophils and monocytes are known to play an important role in tissue damage in ARDS. COVID-19 has been reported to be more severe in patients with hematological malignancies; however, there are few reports of COVID-19 in patients with aplastic anemia. Moreover, how aplastic anemia affects COVID-19 remains unclear. Here, we report the case of a COVID-19 patient with aplastic anemia who had high serum IL-6 levels but did not progress to the severe form of COVID-19. We inferred that severe neutropenia and monocytopenia due to aplastic anemia could contribute to a mild form of COVID-19, although a risk of more severe secondary bacterial infections exists.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:62 |
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| Enthalten in: |
Rinsho ketsueki] The Japanese journal of clinical hematology - 62(2021), 10 vom: 28., Seite 1488-1492 |
| Sprache: |
Japanisch |
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| Beteiligte Personen: |
Murakami, Ken [VerfasserIn] |
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| Links: |
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| Themen: |
Aplastic anemia |
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| Anmerkungen: |
Date Completed 05.11.2021 Date Revised 05.11.2021 published: Print Citation Status MEDLINE |
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| doi: |
10.11406/rinketsu.62.1488 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM332707407 |
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| 500 | |a Date Revised 05.11.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a COVID-19 is a viral infection characterized by a cytokine storm similar to that in acute respiratory distress syndrome (ARDS). Neutrophils and monocytes are known to play an important role in tissue damage in ARDS. COVID-19 has been reported to be more severe in patients with hematological malignancies; however, there are few reports of COVID-19 in patients with aplastic anemia. Moreover, how aplastic anemia affects COVID-19 remains unclear. Here, we report the case of a COVID-19 patient with aplastic anemia who had high serum IL-6 levels but did not progress to the severe form of COVID-19. We inferred that severe neutropenia and monocytopenia due to aplastic anemia could contribute to a mild form of COVID-19, although a risk of more severe secondary bacterial infections exists | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Aplastic anemia | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a IL-6 | |
| 650 | 7 | |a Interleukin-6 |2 NLM | |
| 700 | 1 | |a Yamaguchi, Yuuta |e verfasserin |4 aut | |
| 700 | 1 | |a Kida, Yuko |e verfasserin |4 aut | |
| 700 | 1 | |a Morikawa, Yoichiro |e verfasserin |4 aut | |
| 700 | 1 | |a Ujiie, Hidetoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Sugahara, Hiroyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Kanakura, Yuzuru |e verfasserin |4 aut | |
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