Development of a cooperative autopsy network of pathology, neuropathology and forensic medicine

© 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature..

BACKGROUND: Autopsies are an important tool for understanding novel diseases, including COVID-19.

MATERIALS AND METHODS: The German Registry of COVID-19 Autopsies (DeRegCOVID) was established and launched in April 2020. DeRegCOVID acts as the electronic backbone of the German Network for Autopsies in Pandemics (DEFEAT PANDEMIcs), which started in September 2020.

RESULTS: The results of DeRegCOVID and DEFEAT PANDEMIcs are characterized by an unprecedented collaboration of more than 35 university and non-university autopsy centers linking pathological, neuropathological, and forensic medicine institutes. DeRegCOVID has evolved, adapted to new challenges, and currently contains the largest international autopsy dataset. After only a short period of operation, more than 80 publications have been produced, which have contributed to the understanding of the pathogenesis of COVID-19, e.g., through the discovery of thromboembolic events, multiorgan tropism, and NeuroCovid-19. The autopsy centers have carried out extensive educational work and, beyond the scientific gain in knowledge, have explained to politicians and the general public the essential role of autopsies in pandemic management. To further develop autopsy-driven research, a continuation of DEFEAT PANDEMIcs was conceived, the National Autopsy Network (NATON).

CONCLUSIONS: The registry and network, in which all interested centers can participate, have demonstrated the value of networked medical research and the high value of autopsy for medicine.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:42

Enthalten in:

Der Pathologe - 42(2021), Suppl 2 vom: 01. Dez., Seite 129-134

Sprache:

Deutsch

Weiterer Titel:

Entwicklung eines kooperativen Obduktionsnetzwerks aus Pathologie, Neuropathologie und Rechtsmedizin

Beteiligte Personen:

von Stillfried, Saskia [VerfasserIn]
Boor, Peter [VerfasserIn]
DeRegCOVID und DEFEAT PANDEMIcs [VerfasserIn]

Links:

Volltext

Themen:

Autopsy
Biological specimen banks
COVID-19
Forensic medicine
Journal Article
Review
SARS-CoV‑2

Anmerkungen:

Date Completed 24.12.2021

Date Revised 17.05.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s00292-021-01004-w

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM332526585