Incidental diagnosis of a large cardiac thrombus swinging through an interatrial communication in a COVID-19 patient : Case report and literature review
© 2021 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd..
INTRODUCTION: The hypercoagulability state induced by COVID-19 has been well established and various forms of subsequent thromboembolic events have been reported throughout literature including multiple cases of intracardiac thrombi, four of which in our center alone, this case being the fifth.
CASE REPORT: We report the case of a 38-year-old male with no prior cardiovascular history who -subsequently to a COVID-19 infection-developped a right atrial thrombosis associated to a pulmonary embolism, and in whom cardiography revealed an interatrial communication. Management relied upon curative doses of low molecular weight heparin (LMWH) with favourable outcome.
DISCUSSION: In our discussion, we lay out the various physiopathological mechanisms incriminated throughout literature in the genesis of a hypercoagulability state distinctive of COVID-19, before highlighting the incidence of an interatrial communication (whether a Potent Foramen Ovale or Atrial Septal Defect) discovered in patients with COVID-19, and the potential paradoxical embolization risks they imply as well as reported cases. A mention of hemostatic parameters monitored was also warranted. Finally we discuss the guidelines in terms of prophylactic and therapeutic anticoagulation in hospitalized patients before discussing cardiac thrombosis's therapeutic options.
CONCLUSION: Our case highlights various key points which could change the prognosis of COVID-19 patients, whether related to the underdiagnosis of interatrial abnormalities or with regards to the diagnosis to thromboembolic events, but also the indisputable place of anticoagulation in COVID-19 management.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:71 |
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| Enthalten in: |
Annals of medicine and surgery (2012) - 71(2021) vom: 07. Nov., Seite 102967 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Berrichi, Samia [VerfasserIn] |
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| Anmerkungen: |
Date Revised 27.04.2022 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.amsu.2021.102967 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM332315053 |
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| 500 | |a Date Revised 27.04.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2021 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. | ||
| 520 | |a INTRODUCTION: The hypercoagulability state induced by COVID-19 has been well established and various forms of subsequent thromboembolic events have been reported throughout literature including multiple cases of intracardiac thrombi, four of which in our center alone, this case being the fifth | ||
| 520 | |a CASE REPORT: We report the case of a 38-year-old male with no prior cardiovascular history who -subsequently to a COVID-19 infection-developped a right atrial thrombosis associated to a pulmonary embolism, and in whom cardiography revealed an interatrial communication. Management relied upon curative doses of low molecular weight heparin (LMWH) with favourable outcome | ||
| 520 | |a DISCUSSION: In our discussion, we lay out the various physiopathological mechanisms incriminated throughout literature in the genesis of a hypercoagulability state distinctive of COVID-19, before highlighting the incidence of an interatrial communication (whether a Potent Foramen Ovale or Atrial Septal Defect) discovered in patients with COVID-19, and the potential paradoxical embolization risks they imply as well as reported cases. A mention of hemostatic parameters monitored was also warranted. Finally we discuss the guidelines in terms of prophylactic and therapeutic anticoagulation in hospitalized patients before discussing cardiac thrombosis's therapeutic options | ||
| 520 | |a CONCLUSION: Our case highlights various key points which could change the prognosis of COVID-19 patients, whether related to the underdiagnosis of interatrial abnormalities or with regards to the diagnosis to thromboembolic events, but also the indisputable place of anticoagulation in COVID-19 management | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Cardiac thrombosis | |
| 650 | 4 | |a Interatrial shunt | |
| 700 | 1 | |a Bouayed, Zakaria |e verfasserin |4 aut | |
| 700 | 1 | |a Benbouchta, Karima |e verfasserin |4 aut | |
| 700 | 1 | |a Kossir, Amine |e verfasserin |4 aut | |
| 700 | 1 | |a Bkiyar, Houssam |e verfasserin |4 aut | |
| 700 | 1 | |a Ismaili, Nabila |e verfasserin |4 aut | |
| 700 | 1 | |a Ouafi, Noha El |e verfasserin |4 aut | |
| 700 | 1 | |a Housni, Brahim |e verfasserin |4 aut | |
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