Functional neurological disorder and somatic symptom disorder in Parkinson's disease
Copyright © 2021 Elsevier B.V. All rights reserved..
The occurrence of Functional Neurological Disorder (FND) and Somatic Symptom Disorder (SSD) in PD was not commonly accepted until recently, despite some evidence that emerged in the pre and early L-Dopa era. More recently, the recognition of FND and SSD were noted to be relevant for the management of PD. FND and SSD appear early in the course of PD, often preceding motor symptoms, may interfere with treatment outcomes, often acquire psychotic features during progression, and are mixed with and often concealed by the progressive cognitive decline. We review the related features from the range of the available reports and discuss theoretical models conceived to explain the potential pathophysiological background of these disorders. Finally, we suggest that FND and SSD should be included among the non-motor symptoms of PD and be considered a prodromal feature in a subset of patients. This article is part of the Special Issue "Parkinsonism across the spectrum of movement disorders and beyond" edited by Joseph Jankovic, Daniel D. Truong and Matteo Bologna.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:433 |
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| Enthalten in: |
Journal of the neurological sciences - 433(2022) vom: 15. Feb., Seite 120017 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Onofrj, Marco [VerfasserIn] |
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| Links: |
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| Themen: |
Dementia with Lewy Bodies |
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| Anmerkungen: |
Date Completed 23.03.2022 Date Revised 23.03.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jns.2021.120017 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
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| 520 | |a Copyright © 2021 Elsevier B.V. All rights reserved. | ||
| 520 | |a The occurrence of Functional Neurological Disorder (FND) and Somatic Symptom Disorder (SSD) in PD was not commonly accepted until recently, despite some evidence that emerged in the pre and early L-Dopa era. More recently, the recognition of FND and SSD were noted to be relevant for the management of PD. FND and SSD appear early in the course of PD, often preceding motor symptoms, may interfere with treatment outcomes, often acquire psychotic features during progression, and are mixed with and often concealed by the progressive cognitive decline. We review the related features from the range of the available reports and discuss theoretical models conceived to explain the potential pathophysiological background of these disorders. Finally, we suggest that FND and SSD should be included among the non-motor symptoms of PD and be considered a prodromal feature in a subset of patients. This article is part of the Special Issue "Parkinsonism across the spectrum of movement disorders and beyond" edited by Joseph Jankovic, Daniel D. Truong and Matteo Bologna | ||
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| 650 | 4 | |a Parkinson's disease | |
| 650 | 4 | |a Somatic delusions | |
| 650 | 4 | |a Somatic symptom disorder | |
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| 700 | 1 | |a Espay, Alberto J |e verfasserin |4 aut | |
| 700 | 1 | |a Sensi, Stefano L |e verfasserin |4 aut | |
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