An Overview of the Synthetic Route to the Marketed Formulations of Pyrimidine : A Review
Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net..
Pyrimidine and its derivatives are a very important class of heterocyclic compounds that show interesting applications in the field of medicinal chemistry. Pyrimidine not only plays an important role as an organic reaction intermediate but also has a wide range of interesting biological activities viz. antibacterial, antifungal, anticancer, anti-inflammatory, antiviral, and antiprotozoal activities, etc. Numerous methods are available for the formation of pyrimidine derivatives that have been reported in the literature. The advantage of pyrimidine as a starting material for different therapeutically potent derivatives has given momentum to this research. This review aims to report the new work on the synthesis of marketed drugs which consist pyrimidine moiety.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:22 |
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| Enthalten in: |
Mini reviews in medicinal chemistry - 22(2022), 6 vom: 02., Seite 884-903 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kumar, Amit [VerfasserIn] |
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| Links: |
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| Themen: |
Anticancer |
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| Anmerkungen: |
Date Completed 17.05.2022 Date Revised 17.05.2022 published: Print Citation Status MEDLINE |
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| doi: |
10.2174/1389557521666211008153329 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM331699834 |
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| 520 | |a Pyrimidine and its derivatives are a very important class of heterocyclic compounds that show interesting applications in the field of medicinal chemistry. Pyrimidine not only plays an important role as an organic reaction intermediate but also has a wide range of interesting biological activities viz. antibacterial, antifungal, anticancer, anti-inflammatory, antiviral, and antiprotozoal activities, etc. Numerous methods are available for the formation of pyrimidine derivatives that have been reported in the literature. The advantage of pyrimidine as a starting material for different therapeutically potent derivatives has given momentum to this research. This review aims to report the new work on the synthesis of marketed drugs which consist pyrimidine moiety | ||
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