Adult presentation of multisystem inflammatory syndrome (MIS) associated with recent COVID-19 infection : lessons learnt in timely diagnosis and management
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ..
Multisystem inflammatory syndrome in adults (MIS-A) is an uncommon and under-recognised postinfectious manifestation that presents 4-6 weeks after COVID-19 infection. Patients affected tend to be young or middle-aged, from ethnic minority backgrounds and previously healthy. In addition to high fever and myalgia, there are a myriad of extrapulmonary symptoms and signs, including cardiac, gastrointestinal, neurological and dermatological involvement. Cardiovascular shock and markedly raised inflammatory markers are prominent features, while significant hypoxia is uncommon. Patients respond well to corticosteroid therapy, but failure of clinicians to recognise this recently identified phenomenon, which can mimic common conditions including sepsis, could delay diagnosis and treatment. Here we present a case of MIS-A in an adult woman, compare her presentation and management with other similar case reports, and reflect on how clinicians can learn from our experiences.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
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Enthalten in: |
BMJ case reports - 14(2021), 10 vom: 01. Okt. |
Sprache: |
Englisch |
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Beteiligte Personen: |
Yao, Qiang [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 05.10.2021 Date Revised 04.12.2021 published: Electronic Citation Status MEDLINE |
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doi: |
10.1136/bcr-2021-243114 |
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funding: |
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PPN (Katalog-ID): |
NLM331402807 |
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520 | |a Multisystem inflammatory syndrome in adults (MIS-A) is an uncommon and under-recognised postinfectious manifestation that presents 4-6 weeks after COVID-19 infection. Patients affected tend to be young or middle-aged, from ethnic minority backgrounds and previously healthy. In addition to high fever and myalgia, there are a myriad of extrapulmonary symptoms and signs, including cardiac, gastrointestinal, neurological and dermatological involvement. Cardiovascular shock and markedly raised inflammatory markers are prominent features, while significant hypoxia is uncommon. Patients respond well to corticosteroid therapy, but failure of clinicians to recognise this recently identified phenomenon, which can mimic common conditions including sepsis, could delay diagnosis and treatment. Here we present a case of MIS-A in an adult woman, compare her presentation and management with other similar case reports, and reflect on how clinicians can learn from our experiences | ||
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