Asthma and COVID-19 : lessons learned and questions that remain

INTRODUCTION: Asthma is one of the most common chronic diseases worldwide. As a disease of the respiratory tract, the site of entry for the SARS-CoV-2 virus, there may be an important interplay between asthma and COVID-19 disease.

AREAS COVERED: We report asthma prevalence among hospitalized cohorts with COVID-19. Those with non-allergic and severe asthma may be at increased risk of a worsened clinical outcome from COVID-19 infection. We explore the epidemiology of asthma as a risk factor for the severity of COVID-19 infection. We then consider the role COVID-19 may play in leading to exacerbations of asthma. The impact of asthma endotype on outcome is discussed. Lastly, we address the safety of common asthma therapeutics. A literature search was performed with relevant terms for each of the sections of the review using PubMed, Google Scholar, and Medline.

EXPERT OPINION: Asthma diagnosis may be a risk factor for severe COVID-19 especially for those with severe disease or nonallergic phenotypes. COVID-19 does not appear to provoke asthma exacerbations and asthma therapeutics should be continued for patients with exposure to COVID-19. Clearly much regarding this topic remains unknown and we identify some key questions that may be of interest for future researchers.[Figure: see text].

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:15

Enthalten in:

Expert review of respiratory medicine - 15(2021), 11 vom: 12. Nov., Seite 1377-1386

Sprache:

Englisch

Beteiligte Personen:

Howell, Daniel [VerfasserIn]
Verma, Hannah [VerfasserIn]
Ho, Kam Sing [VerfasserIn]
Narasimhan, Bharat [VerfasserIn]
Steiger, David [VerfasserIn]
Rogers, Linda [VerfasserIn]

Links:

Volltext

Themen:

Asthma
Asthma epidemiology
Asthma genetics
Asthma treatment
COVID-19
Journal Article

Anmerkungen:

Date Completed 29.10.2021

Date Revised 29.10.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/17476348.2021.1985763

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM331122901