Frequency and outcomes of gastrointestinal symptoms in patients with Corona Virus Disease-19
© 2021. Indian Society of Gastroenterology..
OBJECTIVES: To characterize the frequency and association of gastrointestinal (GI) symptoms with outcomes in patients with corona virus disease 2019 (COVID-19) admitted to the hospital.
METHODS: Records were retrospectively collected from patients admitted to a tertiary care center in Washington, D.C., with confirmed COVID-19 from March 15, 2020 to July 15, 2020. After adjusting for clinical demographics and comorbidities, multivariate logistic regression analysis was performed.
RESULTS: The most common presenting symptoms of COVID-19 in patients that were admitted to the hospital were cough (38.4%), shortness of breath (37.5%), and fever (34.3%), followed by GI symptoms in 25.9% of patients. The most common GI symptom was diarrhea (12.8%) followed by nausea or vomiting (10.5%), decreased appetite (9.3%), and abdominal pain (3.8%). Patients with diarrhea were more likely to die (odds ratio [OR] 2.750; p = 0.006; confidence interval [CI] 1.329-5.688), be admitted to the intensive care unit (ICU) (OR 2.242; p = 0.019; CI 1.139-4.413), and be intubated (OR 3.155; p = 0.002; CI 1.535-6.487). Additional outcomes analyzed were need for vasopressors, presence of shock, and acute kidney injury. Patients with diarrhea were 2.738 (p = 0.007; CI 1.325-5.658), 2.467 (p = 0.013; CI 1.209-5.035), and 2.694 (p = 0.007; CI 1.305-5.561) times more likely to experience these outcomes, respectively.
CONCLUSIONS: Screening questions should be expanded to include common GI symptoms in patients with COVID-19. Health care providers should note whether their patient is presenting with diarrhea due to the potential implications on disease severity and outcomes.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
|---|---|
| Enthalten in: |
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 40(2021), 5 vom: 27. Okt., Seite 502-511 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Rogers, Hayley K [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Betacoronavirus |
|---|
| Anmerkungen: |
Date Completed 20.01.2022 Date Revised 18.02.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s12664-021-01191-7 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM33110654X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM33110654X | ||
| 003 | DE-627 | ||
| 005 | 20231225212731.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s12664-021-01191-7 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1103.xml |
| 035 | |a (DE-627)NLM33110654X | ||
| 035 | |a (NLM)34569014 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Rogers, Hayley K |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Frequency and outcomes of gastrointestinal symptoms in patients with Corona Virus Disease-19 |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 20.01.2022 | ||
| 500 | |a Date Revised 18.02.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2021. Indian Society of Gastroenterology. | ||
| 520 | |a OBJECTIVES: To characterize the frequency and association of gastrointestinal (GI) symptoms with outcomes in patients with corona virus disease 2019 (COVID-19) admitted to the hospital | ||
| 520 | |a METHODS: Records were retrospectively collected from patients admitted to a tertiary care center in Washington, D.C., with confirmed COVID-19 from March 15, 2020 to July 15, 2020. After adjusting for clinical demographics and comorbidities, multivariate logistic regression analysis was performed | ||
| 520 | |a RESULTS: The most common presenting symptoms of COVID-19 in patients that were admitted to the hospital were cough (38.4%), shortness of breath (37.5%), and fever (34.3%), followed by GI symptoms in 25.9% of patients. The most common GI symptom was diarrhea (12.8%) followed by nausea or vomiting (10.5%), decreased appetite (9.3%), and abdominal pain (3.8%). Patients with diarrhea were more likely to die (odds ratio [OR] 2.750; p = 0.006; confidence interval [CI] 1.329-5.688), be admitted to the intensive care unit (ICU) (OR 2.242; p = 0.019; CI 1.139-4.413), and be intubated (OR 3.155; p = 0.002; CI 1.535-6.487). Additional outcomes analyzed were need for vasopressors, presence of shock, and acute kidney injury. Patients with diarrhea were 2.738 (p = 0.007; CI 1.325-5.658), 2.467 (p = 0.013; CI 1.209-5.035), and 2.694 (p = 0.007; CI 1.305-5.561) times more likely to experience these outcomes, respectively | ||
| 520 | |a CONCLUSIONS: Screening questions should be expanded to include common GI symptoms in patients with COVID-19. Health care providers should note whether their patient is presenting with diarrhea due to the potential implications on disease severity and outcomes | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Betacoronavirus | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Diarrhea | |
| 650 | 4 | |a Hospitalized patients | |
| 650 | 4 | |a Novel conrona virus | |
| 650 | 4 | |a Pandemic | |
| 650 | 4 | |a SARS-CoV-2 | |
| 700 | 1 | |a Choi, WonSeok W |e verfasserin |4 aut | |
| 700 | 1 | |a Gowda, Niraj |e verfasserin |4 aut | |
| 700 | 1 | |a Nawal, Saadia |e verfasserin |4 aut | |
| 700 | 1 | |a Gordon, Brittney |e verfasserin |4 aut | |
| 700 | 1 | |a Onyilofor, Chinelo |e verfasserin |4 aut | |
| 700 | 1 | |a Rogers, Callie M |e verfasserin |4 aut | |
| 700 | 1 | |a Yamane, David |e verfasserin |4 aut | |
| 700 | 1 | |a Borum, Marie L |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology |d 1993 |g 40(2021), 5 vom: 27. Okt., Seite 502-511 |w (DE-627)NLM012713031 |x 0975-0711 |7 nnns |
| 773 | 1 | 8 | |g volume:40 |g year:2021 |g number:5 |g day:27 |g month:10 |g pages:502-511 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s12664-021-01191-7 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 40 |j 2021 |e 5 |b 27 |c 10 |h 502-511 | ||