Analysis of chemical contamination by hazardous drugs with BD HD Check® system in a tertiary hospital

The presence of contamination in the healthcare work environment by one of the types of hazardous drugs, cytostatics, has been found in multiple international studies. Recent studies and guidelines recommend surface monitoring for risk assessment of healthcare professionals' exposure. The availability of detection techniques is critical to successfully carry out this type of monitoring. The use of new semi-quantitative techniques allows quicker results. The main objective of this study was to determine the existence of hazardous drugs on the working surfaces in different locations of a tertiary hospital using the BD HD Check® semi-quantitative device. The presence of methotrexate, doxorubicin and cyclophosphamide was analysed at 80, 89 and 82 locations in 10, 13 and 11 clinical units, respectively. A total of 251 samples were analysed. The monitoring results were positive for 13.1% of the analysed samples, with 36.3% of the methotrexate samples, 0% of the doxorubicin samples and 4.9% of the cyclophosphamide samples. Mapping the presence of HD in our hospital has allowed us to evaluate the effectiveness of controls established in the hospital to minimise the exposure of healthcare professionals to hazardous drugs. The speed in obtaining results has enabled immediate corrective actions in cases where contaminated surfaces were detected.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:28

Enthalten in:

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners - 28(2022), 7 vom: 15. Okt., Seite 1583-1593

Sprache:

Englisch

Beteiligte Personen:

Valero García, Silvia [VerfasserIn]
Centelles-Oria, María [VerfasserIn]
Palanques-Pastor, Tomás [VerfasserIn]
Vila Clérigues, Nieves [VerfasserIn]
López-Briz, Eduardo [VerfasserIn]
Poveda Andrés, José Luis [VerfasserIn]

Links:

Volltext

Themen:

80168379AG
8N3DW7272P
Antineoplastic Agents
Chemical contamination
Cyclophosphamide
Doxorubicin
Hazardous drugs
Journal Article
Methotrexate
Occupational exposure
Surface monitoring
YL5FZ2Y5U1

Anmerkungen:

Date Completed 12.09.2022

Date Revised 12.09.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/10781552211038518

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM331068907