Accuracy of a Rapid Multiplex Polymerase Chain Reaction Plus a Chromogenic Phenotypic Test Algorithm for Detection of Extended-Spectrum β-Lactamase and Carbapenemase-Producing Gram-Negative Bacilli in Positive Blood Culture Bottles
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissionsoup.com..
We studied the performance of an algorithm combining multiplex polymerase chain reaction with phenotypic detection of extended-spectrum β-lactamases and carbapenemases directly from positive blood culture bottles in patients with gram-negative bacteremia and found good concordance with routine cultures. Such an algorithm may be a tool to improve time to optimal therapy in patients with gram-negative bacteremia.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:74 |
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| Enthalten in: |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 74(2022), 10 vom: 30. Mai, Seite 1850-1854 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ong, Sean Wei Xiang [VerfasserIn] |
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| Links: |
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| Themen: |
Antimicrobial resistance |
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| Anmerkungen: |
Date Completed 02.06.2022 Date Revised 21.06.2022 published: Print ClinicalTrials.gov: NCT02743585 Citation Status MEDLINE |
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| doi: |
10.1093/cid/ciab848 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM330959824 |
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| 245 | 1 | 0 | |a Accuracy of a Rapid Multiplex Polymerase Chain Reaction Plus a Chromogenic Phenotypic Test Algorithm for Detection of Extended-Spectrum β-Lactamase and Carbapenemase-Producing Gram-Negative Bacilli in Positive Blood Culture Bottles |
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| 520 | |a We studied the performance of an algorithm combining multiplex polymerase chain reaction with phenotypic detection of extended-spectrum β-lactamases and carbapenemases directly from positive blood culture bottles in patients with gram-negative bacteremia and found good concordance with routine cultures. Such an algorithm may be a tool to improve time to optimal therapy in patients with gram-negative bacteremia | ||
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| 700 | 1 | |a Mendis, Shehara |e verfasserin |4 aut | |
| 700 | 1 | |a Izharuddin, Ezlyn |e verfasserin |4 aut | |
| 700 | 1 | |a Lin, Ray Junhao |e verfasserin |4 aut | |
| 700 | 1 | |a Chia, Po Ying |e verfasserin |4 aut | |
| 700 | 1 | |a Sim, Rees Chin Swee |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Mark I-Cheng |e verfasserin |4 aut | |
| 700 | 1 | |a Chow, Angela |e verfasserin |4 aut | |
| 700 | 1 | |a Yoong, Joanne |e verfasserin |4 aut | |
| 700 | 1 | |a Lye, David Chien |e verfasserin |4 aut | |
| 700 | 1 | |a Teng, Christine B |e verfasserin |4 aut | |
| 700 | 1 | |a Tambyah, Paul Anantharajah |e verfasserin |4 aut | |
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| 700 | 1 | |a De, Partha Pratim |e verfasserin |4 aut | |
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