Impact of In-Hospital infection with SARS-CoV-2 among Inpatients at a university hospital
Copyright © 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved..
OBJECTIVE: The objective of this study was to evaluate the incidence of nosocomial infection and the impact of cross-transmission of SARS-CoV-2 among inpatients at a tertiary care teaching hospital.
METHODS: This was a retrospective cohort study involving inpatients admitted to a tertiary university hospital in the city of São Paulo, Brazil, between March 2020 and February 2021. Cases were identified on the basis of a positive reverse-transcription polymerase chain reaction result for SARS-CoV-2 and the review of electronic medical records. Nosocomial transmission was defined by applying the criteria established by the Brazilian National Health Regulatory Agency.
RESULTS: We identified 2146 cases of SARS-CoV-2 infection, 185 (8.6%) of which were considered cases of nosocomial transmission. The mean age was 58.3 years. The incidence density was 1.78 cases per 1,000 patient-days on the general wards, being highest on the cardiac surgery ward, and only 0.16 per 1,000 patient-days on the COVID-19 wards. Of the 185 patients evaluated, 115 (62.2%) were men, 150 (81.1%) cases had at least one comorbidity, and 104 (56.2%) evolved to death.
CONCLUSIONS: Despite the preventive measures taken, nosocomial transmission of SARS-CoV-2 occurred throughout our hospital. Such measures should be intensified when the incidence of community transmission peaks.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:49 |
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| Enthalten in: |
American journal of infection control - 49(2021), 12 vom: 22. Dez., Seite 1464-1468 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Tauffer, Josni [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 24.11.2021 Date Revised 03.04.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ajic.2021.09.015 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM330931059 |
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| 245 | 1 | 0 | |a Impact of In-Hospital infection with SARS-CoV-2 among Inpatients at a university hospital |
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| 500 | |a Date Revised 03.04.2024 | ||
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a OBJECTIVE: The objective of this study was to evaluate the incidence of nosocomial infection and the impact of cross-transmission of SARS-CoV-2 among inpatients at a tertiary care teaching hospital | ||
| 520 | |a METHODS: This was a retrospective cohort study involving inpatients admitted to a tertiary university hospital in the city of São Paulo, Brazil, between March 2020 and February 2021. Cases were identified on the basis of a positive reverse-transcription polymerase chain reaction result for SARS-CoV-2 and the review of electronic medical records. Nosocomial transmission was defined by applying the criteria established by the Brazilian National Health Regulatory Agency | ||
| 520 | |a RESULTS: We identified 2146 cases of SARS-CoV-2 infection, 185 (8.6%) of which were considered cases of nosocomial transmission. The mean age was 58.3 years. The incidence density was 1.78 cases per 1,000 patient-days on the general wards, being highest on the cardiac surgery ward, and only 0.16 per 1,000 patient-days on the COVID-19 wards. Of the 185 patients evaluated, 115 (62.2%) were men, 150 (81.1%) cases had at least one comorbidity, and 104 (56.2%) evolved to death | ||
| 520 | |a CONCLUSIONS: Despite the preventive measures taken, nosocomial transmission of SARS-CoV-2 occurred throughout our hospital. Such measures should be intensified when the incidence of community transmission peaks | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Cross infection | |
| 650 | 4 | |a Healthcare-associated infection | |
| 650 | 4 | |a Infection prevention and control | |
| 650 | 4 | |a Infectious disease | |
| 650 | 4 | |a Infectology | |
| 700 | 1 | |a Konstantyner, Thais Claudia Roma de Oliveira |e verfasserin |4 aut | |
| 700 | 1 | |a de Almeida, Maria Claudia Stockler |e verfasserin |4 aut | |
| 700 | 1 | |a Ferreira, Diogo Boldim |e verfasserin |4 aut | |
| 700 | 1 | |a Antonelli, Thaysa Sobral |e verfasserin |4 aut | |
| 700 | 1 | |a Fram, Dayana Souza |e verfasserin |4 aut | |
| 700 | 1 | |a Escudero, Daniela Vieira |e verfasserin |4 aut | |
| 700 | 1 | |a Ferreira, Paulo Roberto Abrão |e verfasserin |4 aut | |
| 700 | 1 | |a Bellei, Nancy |e verfasserin |4 aut | |
| 700 | 1 | |a Colombo, Arnaldo Lopes |e verfasserin |4 aut | |
| 700 | 1 | |a Yashiro, Suely Miyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Machado, Antonia Maria de Oliveira |e verfasserin |4 aut | |
| 700 | 1 | |a Medeiros, Eduardo Alexandrino |e verfasserin |4 aut | |
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