The influence of advanced age in bone healing after intramedullary limb lengthening
Copyright © 2021 The Author(s). Published by Elsevier Masson SAS.. All rights reserved..
BACKGROUND: Distraction osteogenesis with an intramedullary motorized nail is a well-established method to treat leg length discrepancy (LLD). The complex process of bone consolidation is affected by age, location, comorbidities, smoking and gender. The purpose of this case series was to investigate influencing factors in bone regeneration after intramedullary callus distraction.
HYPOTHESIS: Advanced age influences the outcome of intramedullary limb lengthening.
PATIENTS AND METHODS: This retrospective analysis included 19 patients after intramedullary telescopic nailing (PRECICE) on the lower limb with a mean age of 43 years. Bone healing was assessed by distraction and healing parameters such as distraction-consolidation time (DCT), distraction index (DI), healing index (HI), lengthening index (LI), and consolidation index (CI).
RESULTS: Confounding factors such as smoking, previous operations on the treated bone, but also the occurrence of complications, and the number of revision surgeries are independent of the patients' age. Younger patients showed a shorter distraction distance, a lower DCT, a lower DI, a higher HI, and a higher CI than older patients. The complication rate requiring nail exchange was higher among the younger patients. Bony healing was observed in all age groups treated with a telescopic nail regardless of age.
CONCLUSION: Advanced age did not influence bone healing or complication rate in intramedullary lengthening. However, the conclusion is limited by the small patient number.
LEVEL OF EVIDENCE: IV; Case control study.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:107 |
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| Enthalten in: |
Orthopaedics & traumatology, surgery & research : OTSR - 107(2021), 8 vom: 30. Dez., Seite 103055 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zak, Lukas [VerfasserIn] |
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| Links: |
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| Themen: |
Distraction osteogenesis |
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| Anmerkungen: |
Date Completed 10.03.2022 Date Revised 11.03.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.otsr.2021.103055 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM330785222 |
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| 100 | 1 | |a Zak, Lukas |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The influence of advanced age in bone healing after intramedullary limb lengthening |
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| 500 | |a Date Completed 10.03.2022 | ||
| 500 | |a Date Revised 11.03.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 The Author(s). Published by Elsevier Masson SAS.. All rights reserved. | ||
| 520 | |a BACKGROUND: Distraction osteogenesis with an intramedullary motorized nail is a well-established method to treat leg length discrepancy (LLD). The complex process of bone consolidation is affected by age, location, comorbidities, smoking and gender. The purpose of this case series was to investigate influencing factors in bone regeneration after intramedullary callus distraction | ||
| 520 | |a HYPOTHESIS: Advanced age influences the outcome of intramedullary limb lengthening | ||
| 520 | |a PATIENTS AND METHODS: This retrospective analysis included 19 patients after intramedullary telescopic nailing (PRECICE) on the lower limb with a mean age of 43 years. Bone healing was assessed by distraction and healing parameters such as distraction-consolidation time (DCT), distraction index (DI), healing index (HI), lengthening index (LI), and consolidation index (CI) | ||
| 520 | |a RESULTS: Confounding factors such as smoking, previous operations on the treated bone, but also the occurrence of complications, and the number of revision surgeries are independent of the patients' age. Younger patients showed a shorter distraction distance, a lower DCT, a lower DI, a higher HI, and a higher CI than older patients. The complication rate requiring nail exchange was higher among the younger patients. Bony healing was observed in all age groups treated with a telescopic nail regardless of age | ||
| 520 | |a CONCLUSION: Advanced age did not influence bone healing or complication rate in intramedullary lengthening. However, the conclusion is limited by the small patient number | ||
| 520 | |a LEVEL OF EVIDENCE: IV; Case control study | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Distraction osteogenesis | |
| 650 | 4 | |a Intramedullary limb lengthening | |
| 700 | 1 | |a Arnhold, Richard |e verfasserin |4 aut | |
| 700 | 1 | |a Tiefenboeck, Thomas M |e verfasserin |4 aut | |
| 700 | 1 | |a Wozasek, Gerald E |e verfasserin |4 aut | |
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