Study of Aqueous Ecballium Elaterium as Fibrinolytic in The Rabbit Model of Intrapleural Empyema
AIMS: We aimed to investigate of intrapleural use of ecballium elaterium (EE) in a rabbit model empyema.
METHODS: An empyema was induced in 21 rabbits after inoculation of Staphylococcus aureus. Glucose levels, pH, lactate dehydrogenase levels, and amounts of pleural drainage were evaluated in addition to pleural and empyema scores. The rabbits were divided into three groups, each 7, the isotonic solution, the streptokinase, and the ecballium group.
RESULTS: At autopsy, there was no difference in pH, glucose, and LDH levels in three groups. The mean pleural drainage was greater in the ecballium group. A significant difference was detected between groups in terms of drainage amounts and pleural and empyema scores (P < 0.05). A significant difference in pleural and empyema scores was detected in the ecballium and streptokinase groups (P < 0.05). EE group had significant differences in drainage amounts and plural and empyema scores regard to the control group (P < 0.05). No significance was found between streptokinase and EE groups.
CONCLUSION: We conclude that intrapleural use of EE is at least as effective as streptokinase for the treatment of empyema.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
|---|---|
| Enthalten in: |
Nigerian journal of clinical practice - 24(2021), 9 vom: 16. Sept., Seite 1326-1331 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Sahin, A [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
EC 3.4.- |
|---|
| Anmerkungen: |
Date Completed 20.09.2021 Date Revised 26.04.2022 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.4103/njcp.njcp_360_20 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM33073315X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM33073315X | ||
| 003 | DE-627 | ||
| 005 | 20231225211922.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.4103/njcp.njcp_360_20 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1102.xml |
| 035 | |a (DE-627)NLM33073315X | ||
| 035 | |a (NLM)34531345 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Sahin, A |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Study of Aqueous Ecballium Elaterium as Fibrinolytic in The Rabbit Model of Intrapleural Empyema |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 20.09.2021 | ||
| 500 | |a Date Revised 26.04.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a AIMS: We aimed to investigate of intrapleural use of ecballium elaterium (EE) in a rabbit model empyema | ||
| 520 | |a METHODS: An empyema was induced in 21 rabbits after inoculation of Staphylococcus aureus. Glucose levels, pH, lactate dehydrogenase levels, and amounts of pleural drainage were evaluated in addition to pleural and empyema scores. The rabbits were divided into three groups, each 7, the isotonic solution, the streptokinase, and the ecballium group | ||
| 520 | |a RESULTS: At autopsy, there was no difference in pH, glucose, and LDH levels in three groups. The mean pleural drainage was greater in the ecballium group. A significant difference was detected between groups in terms of drainage amounts and pleural and empyema scores (P < 0.05). A significant difference in pleural and empyema scores was detected in the ecballium and streptokinase groups (P < 0.05). EE group had significant differences in drainage amounts and plural and empyema scores regard to the control group (P < 0.05). No significance was found between streptokinase and EE groups | ||
| 520 | |a CONCLUSION: We conclude that intrapleural use of EE is at least as effective as streptokinase for the treatment of empyema | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Ecballium | |
| 650 | 4 | |a empyema | |
| 650 | 4 | |a fibrinolytics | |
| 650 | 4 | |a streptokinase | |
| 650 | 7 | |a Fibrinolytic Agents |2 NLM | |
| 650 | 7 | |a Streptokinase |2 NLM | |
| 650 | 7 | |a EC 3.4.- |2 NLM | |
| 700 | 1 | |a Oruc, M |e verfasserin |4 aut | |
| 700 | 1 | |a Meteroğlu, F |e verfasserin |4 aut | |
| 700 | 1 | |a Erbey, A |e verfasserin |4 aut | |
| 700 | 1 | |a Alabalık, U |e verfasserin |4 aut | |
| 700 | 1 | |a Kaplan, I |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nigerian journal of clinical practice |d 2005 |g 24(2021), 9 vom: 16. Sept., Seite 1326-1331 |w (DE-627)NLM159917247 |x 1119-3077 |7 nnns |
| 773 | 1 | 8 | |g volume:24 |g year:2021 |g number:9 |g day:16 |g month:09 |g pages:1326-1331 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.4103/njcp.njcp_360_20 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 24 |j 2021 |e 9 |b 16 |c 09 |h 1326-1331 | ||