Can we trust in Sars-CoV-2 rapid antigen testing? Preliminary results from a paediatric cohort in the emergency department
© 2021. Royal Academy of Medicine in Ireland..
BACKGROUND: Rapid identification of Covid-19 in the paediatric emergency department is critical; Antigen tests are fast but poorly investigated in children.
AIMS: To investigate Sars-CoV-2 antigen rapid test in children.
METHODS: We compare the performance of LumiraDx with molecular tests in a paediatric emergency department.
RESULTS: A retrospective cohort of 191 patients with AT and PCR tests performed in the same episode was analysed; 16% resulted positive for Sars-CoV-2. Using the PCR test as the gold standard, we calculated antigen testing overall sensitivity of 94.1%, specificity of 91.9%, and NPV of 99.4%. Only one false-negative test was found.
CONCLUSIONS: AT may be helpful in the initial screening of patients at PED.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:191 |
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| Enthalten in: |
Irish journal of medical science - 191(2022), 4 vom: 14. Aug., Seite 1767-1770 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Denina, Marco [VerfasserIn] |
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| Links: |
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| Themen: |
Antigen tests |
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| Anmerkungen: |
Date Completed 26.07.2022 Date Revised 26.07.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s11845-021-02776-z |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM330620355 |
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| 500 | |a Date Revised 26.07.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2021. Royal Academy of Medicine in Ireland. | ||
| 520 | |a BACKGROUND: Rapid identification of Covid-19 in the paediatric emergency department is critical; Antigen tests are fast but poorly investigated in children | ||
| 520 | |a AIMS: To investigate Sars-CoV-2 antigen rapid test in children | ||
| 520 | |a METHODS: We compare the performance of LumiraDx with molecular tests in a paediatric emergency department | ||
| 520 | |a RESULTS: A retrospective cohort of 191 patients with AT and PCR tests performed in the same episode was analysed; 16% resulted positive for Sars-CoV-2. Using the PCR test as the gold standard, we calculated antigen testing overall sensitivity of 94.1%, specificity of 91.9%, and NPV of 99.4%. Only one false-negative test was found | ||
| 520 | |a CONCLUSIONS: AT may be helpful in the initial screening of patients at PED | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Antigen tests | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Emergency department | |
| 650 | 4 | |a Point-of-care tests | |
| 650 | 4 | |a Sars-Cov-2 | |
| 700 | 1 | |a Giannone, Virginia |e verfasserin |4 aut | |
| 700 | 1 | |a Curtoni, Antonio |e verfasserin |4 aut | |
| 700 | 1 | |a Zanotto, Elisa |e verfasserin |4 aut | |
| 700 | 1 | |a Garazzino, Silvia |e verfasserin |4 aut | |
| 700 | 1 | |a Urbino, Antonio Francesco |e verfasserin |4 aut | |
| 700 | 1 | |a Bondone, Claudia |e verfasserin |4 aut | |
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