Coronavirus disease 2019 outcomes in heart transplant recipients : a single-center case series

© 2021. The Author(s)..

BACKGROUND: With the rapidly expanding pandemic of severe acute respiratory syndrome coronavirus-2, a chronic immunosuppressed state in solid organ transplant recipients is a concern. We reported coronavirus disease 2019 in heart transplant recipients and described the patients' course from diagnosis to either hospital admission or improvement in symptoms.

CASE PRESENTATION: This study retrospectively identified 13 white (Iranian) heart transplant patients with coronavirus disease 2019 between December 2019 and October 2020. The mean age of patients was 43.7 years (19-65 years); seven (70%) were men. Laboratory and treatment data were collected for those admitted or managed as outpatients. Outcomes were also recorded for all patients. This report demonstrates a range of symptoms, clinical severity, and disease course in heart transplant recipients with coronavirus disease 2019, including ten hospitalized patients and three patients, managed entirely in the outpatient setting. One patient passed away, and none of them experienced an episode of clinically overt rejection.

CONCLUSIONS: We would like to emphasize the importance of being alert in these patients to consider testing in a broad range of clinical presentations and gathering more data for better management.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:15

Enthalten in:

Journal of medical case reports - 15(2021), 1 vom: 13. Sept., Seite 453

Sprache:

Englisch

Beteiligte Personen:

Naghashzadeh, Farah [VerfasserIn]
Shafaghi, Shadi [VerfasserIn]
Sharif-Kashani, Babak [VerfasserIn]
Tabarsi, Payam [VerfasserIn]
Saliminejad, Leila [VerfasserIn]
Noorali, Sima [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Case Reports
Heart transplantation
Immunosuppression
Immunosuppressive Agents
Journal Article
Solid-organ transplantation

Anmerkungen:

Date Completed 14.09.2021

Date Revised 16.09.2021

published: Electronic

Citation Status MEDLINE

doi:

10.1186/s13256-021-03028-5

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM330533088