Prevalence and clinical consequences of atelectasis in SARS-CoV-2 pneumonia : a computed tomography retrospective cohort study
© 2021. The Author(s)..
BACKGROUND: The aim of the study is to estimate the prevalence of atelectasis assessed with computer tomography (CT) in SARS-CoV-2 pneumonia and the relationship between the amount of atelectasis with oxygenation impairment, Intensive Care Unit admission rate and the length of in-hospital stay.
PATIENTS AND METHODS: Two-hundred thirty-seven patients admitted to the hospital with SARS-CoV-2 pneumonia diagnosed by clinical, radiology and molecular tests in the nasopharyngeal swab who underwent a chest computed tomography because of a respiratory worsening from Apr 1 to Apr 30, 2020 were included in the study. Patients were divided into three groups depending on the presence and amount of atelectasis at the computed tomography: no atelectasis, small atelectasis (< 5% of the estimated lung volume) or large atelectasis (> 5% of the estimated lung volume). In all patients, clinical severity, oxygen-therapy need, Intensive Care Unit admission rate, the length of in-hospital stay and in-hospital mortality data were collected.
RESULTS: Thirty patients (19%) showed small atelectasis while eight patients (5%) showed large atelectasis. One hundred and seventeen patients (76%) did not show atelectasis. Patients with large atelectasis compared to patients with small atelectasis had lower SatO2/FiO2 (182 vs 411 respectively, p = 0.01), needed more days of oxygen therapy (20 vs 5 days respectively, p = 0,02), more frequently Intensive Care Unit admission (75% vs 7% respectively, p < 0.01) and a longer period of hospitalization (40 vs 14 days respectively p < 0.01).
CONCLUSION: In patients with SARS-CoV-2 pneumonia, atelectasis might appear in up to 24% of patients and the presence of larger amount of atelectasis is associated with worse oxygenation and clinical outcome.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2021 |
---|---|
Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
---|---|
Enthalten in: |
BMC pulmonary medicine - 21(2021), 1 vom: 17. Aug., Seite 267 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Mingote, Álvaro [VerfasserIn] |
---|
Links: |
---|
Themen: |
Atelectasis |
---|
Anmerkungen: |
Date Completed 30.08.2021 Date Revised 03.04.2024 published: Electronic Citation Status MEDLINE |
---|
doi: |
10.1186/s12890-021-01638-9 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM329479644 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | NLM329479644 | ||
003 | DE-627 | ||
005 | 20240403232856.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2021 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1186/s12890-021-01638-9 |2 doi | |
028 | 5 | 2 | |a pubmed24n1362.xml |
035 | |a (DE-627)NLM329479644 | ||
035 | |a (NLM)34404383 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Mingote, Álvaro |e verfasserin |4 aut | |
245 | 1 | 0 | |a Prevalence and clinical consequences of atelectasis in SARS-CoV-2 pneumonia |b a computed tomography retrospective cohort study |
264 | 1 | |c 2021 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 30.08.2021 | ||
500 | |a Date Revised 03.04.2024 | ||
500 | |a published: Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a © 2021. The Author(s). | ||
520 | |a BACKGROUND: The aim of the study is to estimate the prevalence of atelectasis assessed with computer tomography (CT) in SARS-CoV-2 pneumonia and the relationship between the amount of atelectasis with oxygenation impairment, Intensive Care Unit admission rate and the length of in-hospital stay | ||
520 | |a PATIENTS AND METHODS: Two-hundred thirty-seven patients admitted to the hospital with SARS-CoV-2 pneumonia diagnosed by clinical, radiology and molecular tests in the nasopharyngeal swab who underwent a chest computed tomography because of a respiratory worsening from Apr 1 to Apr 30, 2020 were included in the study. Patients were divided into three groups depending on the presence and amount of atelectasis at the computed tomography: no atelectasis, small atelectasis (< 5% of the estimated lung volume) or large atelectasis (> 5% of the estimated lung volume). In all patients, clinical severity, oxygen-therapy need, Intensive Care Unit admission rate, the length of in-hospital stay and in-hospital mortality data were collected | ||
520 | |a RESULTS: Thirty patients (19%) showed small atelectasis while eight patients (5%) showed large atelectasis. One hundred and seventeen patients (76%) did not show atelectasis. Patients with large atelectasis compared to patients with small atelectasis had lower SatO2/FiO2 (182 vs 411 respectively, p = 0.01), needed more days of oxygen therapy (20 vs 5 days respectively, p = 0,02), more frequently Intensive Care Unit admission (75% vs 7% respectively, p < 0.01) and a longer period of hospitalization (40 vs 14 days respectively p < 0.01) | ||
520 | |a CONCLUSION: In patients with SARS-CoV-2 pneumonia, atelectasis might appear in up to 24% of patients and the presence of larger amount of atelectasis is associated with worse oxygenation and clinical outcome | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Atelectasis | |
650 | 4 | |a Chest computed tomography | |
650 | 4 | |a Coronavirus | |
650 | 4 | |a Mechanical ventilation | |
650 | 4 | |a Severe acute respiratory syndrome | |
700 | 1 | |a Albajar, Andrea |e verfasserin |4 aut | |
700 | 1 | |a García Benedito, Paulino |e verfasserin |4 aut | |
700 | 1 | |a Garcia-Suarez, Jessica |e verfasserin |4 aut | |
700 | 1 | |a Pelosi, Paolo |e verfasserin |4 aut | |
700 | 1 | |a Ball, Lorenzo |e verfasserin |4 aut | |
700 | 1 | |a García-Fernández, Javier |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t BMC pulmonary medicine |d 2001 |g 21(2021), 1 vom: 17. Aug., Seite 267 |w (DE-627)NLM114960313 |x 1471-2466 |7 nnns |
773 | 1 | 8 | |g volume:21 |g year:2021 |g number:1 |g day:17 |g month:08 |g pages:267 |
856 | 4 | 0 | |u http://dx.doi.org/10.1186/s12890-021-01638-9 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 21 |j 2021 |e 1 |b 17 |c 08 |h 267 |