Identification and infection control of carbapenem-resistant Enterobacterales in intensive care units

Infections with multidrug-resistant organisms among patients in intensive care units (ICUs) are associated with high mortality. Among multidrug-resistant organisms, carbapenem-resistant Enterobacterales (CRE) harbor important pathogens for healthcare-associated infections, including pneumonia, bacteremia, and urinary tract infections. Risk factors for CRE colonization include underlying comorbid conditions, prior antibiotics exposure, prior use of healthcare facilities, device use, and longer ICU stay. The mortality rate due to invasive CRE infection is 22%-49%, and CRE colonization is associated with an approximately 10-fold increased risk of CRE infection. Infection control measures include hand hygiene, contact precautions, minimizing the use of devices, and environmental control. Additionally, implementing active surveillance of CRE carriage should be considered in ICU settings.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:36

Enthalten in:

Acute and critical care - 36(2021), 3 vom: 10. Aug., Seite 175-184

Sprache:

Englisch

Beteiligte Personen:

Yi, Jongyoun [VerfasserIn]
Kim, Kye-Hyung [VerfasserIn]

Links:

Volltext

Themen:

Carbapenem
Carbapenem-resistant enterobacteriaceae
Drug resistance
Infection control
Intensive care units
Journal Article

Anmerkungen:

Date Revised 21.09.2021

published: Print-Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.4266/acc.2021.00409

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM329240870