The seroprevalence of severe acute respiratory syndrome coronavirus 2 in Delhi, India : a repeated population-based seroepidemiological study
© The Author(s) 2021. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene..
BACKGROUND: Three rounds of a repeated cross-sectional serosurvey to estimate the change in seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were conducted from August to October 2020 in the state of Delhi, India, in the general population ≥5 y of age.
METHODS: The selection of participants was through a multistage sampling design from all 11 districts and 280 wards of the city-state, with multistage allocation proportional to population size. The blood samples were screened using immunoglobulin G (IgG) enzyme-linked immunosorbent assay kits.
RESULTS: We observed a total of 4267 (N=150 46), 4311 (N=17 409) and 3829 (N=15 015) positive tests indicative of the presence of IgG antibody to SARS-CoV-2 during the August, September and October 2020 serosurvey rounds, respectively. The adjusted seroprevalence declined from 28.39% (95% confidence interval [CI] 27.65 to 29.14) in August to 24.08% (95% CI 23.43 to 24.74) in September and 24.71% (95% CI 24.01 to 25.42) in October. On adjusted analysis, participants with lower per capita income, living in slums or overcrowded households and those with diabetes comorbidity had significantly higher statistical odds of having antibody positivity (p<0.01).
CONCLUSIONS: Nearly one in four residents in Delhi, India ≥5 y of age had the SARS-CoV-2 infection during August-October 2020.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:116 |
|---|---|
| Enthalten in: |
Transactions of the Royal Society of Tropical Medicine and Hygiene - 116(2022), 3 vom: 02. März, Seite 242-251 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Sharma, Nandini [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Antibodies, Viral |
|---|
| Anmerkungen: |
Date Completed 09.03.2022 Date Revised 09.03.2022 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1093/trstmh/trab109 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM328840262 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM328840262 | ||
| 003 | DE-627 | ||
| 005 | 20231225203817.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1093/trstmh/trab109 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1096.xml |
| 035 | |a (DE-627)NLM328840262 | ||
| 035 | |a (NLM)34339514 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Sharma, Nandini |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The seroprevalence of severe acute respiratory syndrome coronavirus 2 in Delhi, India |b a repeated population-based seroepidemiological study |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 09.03.2022 | ||
| 500 | |a Date Revised 09.03.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © The Author(s) 2021. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. | ||
| 520 | |a BACKGROUND: Three rounds of a repeated cross-sectional serosurvey to estimate the change in seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were conducted from August to October 2020 in the state of Delhi, India, in the general population ≥5 y of age | ||
| 520 | |a METHODS: The selection of participants was through a multistage sampling design from all 11 districts and 280 wards of the city-state, with multistage allocation proportional to population size. The blood samples were screened using immunoglobulin G (IgG) enzyme-linked immunosorbent assay kits | ||
| 520 | |a RESULTS: We observed a total of 4267 (N=150 46), 4311 (N=17 409) and 3829 (N=15 015) positive tests indicative of the presence of IgG antibody to SARS-CoV-2 during the August, September and October 2020 serosurvey rounds, respectively. The adjusted seroprevalence declined from 28.39% (95% confidence interval [CI] 27.65 to 29.14) in August to 24.08% (95% CI 23.43 to 24.74) in September and 24.71% (95% CI 24.01 to 25.42) in October. On adjusted analysis, participants with lower per capita income, living in slums or overcrowded households and those with diabetes comorbidity had significantly higher statistical odds of having antibody positivity (p<0.01) | ||
| 520 | |a CONCLUSIONS: Nearly one in four residents in Delhi, India ≥5 y of age had the SARS-CoV-2 infection during August-October 2020 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a serosurvey | |
| 650 | 7 | |a Antibodies, Viral |2 NLM | |
| 700 | 1 | |a Sharma, Pragya |e verfasserin |4 aut | |
| 700 | 1 | |a Basu, Saurav |e verfasserin |4 aut | |
| 700 | 1 | |a Saxena, Sonal |e verfasserin |4 aut | |
| 700 | 1 | |a Chawla, Rohit |e verfasserin |4 aut | |
| 700 | 1 | |a Dushyant, Kumar |e verfasserin |4 aut | |
| 700 | 1 | |a Mundeja, Nutan |e verfasserin |4 aut | |
| 700 | 1 | |a Marak, Zeasaly |e verfasserin |4 aut | |
| 700 | 1 | |a Singh, Sanjay |e verfasserin |4 aut | |
| 700 | 1 | |a Singh, Gautam |e verfasserin |4 aut | |
| 700 | 1 | |a Rustagi, Ruchir |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Transactions of the Royal Society of Tropical Medicine and Hygiene |d 1945 |g 116(2022), 3 vom: 02. März, Seite 242-251 |w (DE-627)NLM000035653 |x 1878-3503 |7 nnns |
| 773 | 1 | 8 | |g volume:116 |g year:2022 |g number:3 |g day:02 |g month:03 |g pages:242-251 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1093/trstmh/trab109 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 116 |j 2022 |e 3 |b 02 |c 03 |h 242-251 | ||