The genetic structure of SARS-CoV-2 is consistent with both natural or laboratory origin : Response to Tyshkovskiy and Panchin (10.1002/bies.202000325)
© 2021 Wiley Periodicals LLC..
Tyshkovskiy and Panchin have recently published a commentary on our paper in which they outline several "points of disagreement with the Segreto/Deigin hypothesis." As our paper is titled "The genetic structure of SARS-CoV-2 does not rule out a laboratory origin," points of disagreement should provide evidence that rules out a laboratory origin. However, Tyshkovskiy and Panchin provide no such evidence and instead attempt to criticize our arguments that highlight aspects of SARS-CoV-2 that could be consistent with the lab leak hypothesis. Strikingly, Tyshkovskiy and Panchin's main point of criticism is based on a false premise that we have claimed RaTG13 to be a direct progenitor of SARS-CoV-2, and their other points of criticism are either not valid, based on flawed mathematical analysis, or are unrelated to our hypotheses. Thus, the genetic structure of SARS-CoV-2 remains consistent with both natural or laboratory origin, which means that both the zoonotic and the lab leak hypothesis need to be investigated equally thoroughly.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2021 |
---|---|
Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:43 |
---|---|
Enthalten in: |
BioEssays : news and reviews in molecular, cellular and developmental biology - 43(2021), 9 vom: 19. Sept., Seite e2100137 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Deigin, Yuri [VerfasserIn] |
---|
Links: |
---|
Themen: |
Covid origins |
---|
Anmerkungen: |
Date Completed 06.09.2021 Date Revised 06.09.2021 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1002/bies.202100137 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM32872341X |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM32872341X | ||
003 | DE-627 | ||
005 | 20231225203540.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2021 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1002/bies.202100137 |2 doi | |
028 | 5 | 2 | |a pubmed24n1095.xml |
035 | |a (DE-627)NLM32872341X | ||
035 | |a (NLM)34327738 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Deigin, Yuri |e verfasserin |4 aut | |
245 | 1 | 4 | |a The genetic structure of SARS-CoV-2 is consistent with both natural or laboratory origin |b Response to Tyshkovskiy and Panchin (10.1002/bies.202000325) |
264 | 1 | |c 2021 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 06.09.2021 | ||
500 | |a Date Revised 06.09.2021 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a © 2021 Wiley Periodicals LLC. | ||
520 | |a Tyshkovskiy and Panchin have recently published a commentary on our paper in which they outline several "points of disagreement with the Segreto/Deigin hypothesis." As our paper is titled "The genetic structure of SARS-CoV-2 does not rule out a laboratory origin," points of disagreement should provide evidence that rules out a laboratory origin. However, Tyshkovskiy and Panchin provide no such evidence and instead attempt to criticize our arguments that highlight aspects of SARS-CoV-2 that could be consistent with the lab leak hypothesis. Strikingly, Tyshkovskiy and Panchin's main point of criticism is based on a false premise that we have claimed RaTG13 to be a direct progenitor of SARS-CoV-2, and their other points of criticism are either not valid, based on flawed mathematical analysis, or are unrelated to our hypotheses. Thus, the genetic structure of SARS-CoV-2 remains consistent with both natural or laboratory origin, which means that both the zoonotic and the lab leak hypothesis need to be investigated equally thoroughly | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Covid origins | |
650 | 4 | |a Gain-of-function | |
650 | 4 | |a MP789 | |
650 | 4 | |a RaTG13 | |
650 | 4 | |a SARS-CoV-2 | |
650 | 4 | |a furin cleavage site | |
650 | 4 | |a pangolin CoV | |
650 | 7 | |a Spike Glycoprotein, Coronavirus |2 NLM | |
700 | 1 | |a Segreto, Rossana |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t BioEssays : news and reviews in molecular, cellular and developmental biology |d 1993 |g 43(2021), 9 vom: 19. Sept., Seite e2100137 |w (DE-627)NLM012660450 |x 1521-1878 |7 nnns |
773 | 1 | 8 | |g volume:43 |g year:2021 |g number:9 |g day:19 |g month:09 |g pages:e2100137 |
856 | 4 | 0 | |u http://dx.doi.org/10.1002/bies.202100137 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 43 |j 2021 |e 9 |b 19 |c 09 |h e2100137 |