Compendium of Conventional and Targeted Drug Delivery Formulation Used for the Treatment and Management of the Wound Healing

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Wound healing is a complex and dynamic phenomenon that involves the restoration of normal physiology and functioning of injured tissue. The process of wound healing is primarily regulated by various cytokines, inflammatory mediators, and growth factors at the molecular level. Any intervention in the normal wound healing process leads to further tissue damage, which in turn leads to delayed wound healing. Several natural, synthetic drugs and their combinations were used to restore and accelerate the wound healing process. However, the conventional delivery carriers were not much effective, and thus, nowadays, nanocarriers are gaining much popularity since they are playing a pivotal role in drug delivery. Since nanocarriers have their own applicability and benefits (enhance the bioavailability, site-specific targeting) so, they can accelerate wound healing more efficiently. This review briefly discussed about the various events that take place during the wound healing process with emphasis on various natural, synthetic, and combination drug therapy used for accelerating wound healing and the role of nanotechnology-based approaches in chronic wound healing.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:19

Enthalten in:

Current drug delivery - 19(2022), 2 vom: 22., Seite 192-211

Sprache:

Englisch

Beteiligte Personen:

Singh, Ajay [VerfasserIn]
Maqsood, Zeba [VerfasserIn]
Iqubal, Mohammad Kashif [VerfasserIn]
Ali, Javed [VerfasserIn]
Baboota, Sanjula [VerfasserIn]

Links:

Volltext

Themen:

Clinical trial
Combination therapy
Intercellular Signaling Peptides and Proteins
Journal Article
Kinds of wounds
Natural drug
Pharmaceutical Preparations
Phytoconstituents
Review
Wound healing

Anmerkungen:

Date Completed 01.03.2022

Date Revised 01.03.2022

published: Print

Citation Status MEDLINE

doi:

10.2174/1567201818666210727165916

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM328600695