Wound Botulism in Black Tar Heroin Injecting Users : A Case Series
The incidence of wound botulism in injection drug users has increased since the introduction of black tar heroin. Many species of the Clostridium genus, most commonly Clostridium botulinum, Clostridium baratii, and Clostridium butyricum, have been associated with wound botulism. Patients often present with progressive bulbar weakness, including dysphagia, cranial nerve palsies, and loss of speech, in addition to symmetrical descending weakness of the upper extremities that may progress to the chest and lower extremities. In this article, we present 3 cases of wound botulism, in which the patients presented with bulbar weakness and were treated with botulism antitoxin heptavalent. The time to antitoxin administration and its effect on the patients' clinical courses is compared.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
|---|---|
| Enthalten in: |
Journal of investigative medicine high impact case reports - 9(2021) vom: 01. Jan., Seite 23247096211028078 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Raza, Nadia [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
70D95007SX |
|---|
| Anmerkungen: |
Date Completed 15.10.2021 Date Revised 31.10.2023 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1177/23247096211028078 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM328047015 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM328047015 | ||
| 003 | DE-627 | ||
| 005 | 20231225202123.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1177/23247096211028078 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1093.xml |
| 035 | |a (DE-627)NLM328047015 | ||
| 035 | |a (NLM)34259080 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Raza, Nadia |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Wound Botulism in Black Tar Heroin Injecting Users |b A Case Series |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 15.10.2021 | ||
| 500 | |a Date Revised 31.10.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The incidence of wound botulism in injection drug users has increased since the introduction of black tar heroin. Many species of the Clostridium genus, most commonly Clostridium botulinum, Clostridium baratii, and Clostridium butyricum, have been associated with wound botulism. Patients often present with progressive bulbar weakness, including dysphagia, cranial nerve palsies, and loss of speech, in addition to symmetrical descending weakness of the upper extremities that may progress to the chest and lower extremities. In this article, we present 3 cases of wound botulism, in which the patients presented with bulbar weakness and were treated with botulism antitoxin heptavalent. The time to antitoxin administration and its effect on the patients' clinical courses is compared | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Clostridium botulinum | |
| 650 | 4 | |a botulism heptavalent antitoxin | |
| 650 | 4 | |a injection drug users | |
| 650 | 4 | |a wound botulism | |
| 650 | 7 | |a Heroin |2 NLM | |
| 650 | 7 | |a 70D95007SX |2 NLM | |
| 700 | 1 | |a Dhital, Sandhya |e verfasserin |4 aut | |
| 700 | 1 | |a Espinoza, Valerie Elise |e verfasserin |4 aut | |
| 700 | 1 | |a Jariwal, Roopam |e verfasserin |4 aut | |
| 700 | 1 | |a Chiu, Chien-Wai |e verfasserin |4 aut | |
| 700 | 1 | |a Valdez, Michael |e verfasserin |4 aut | |
| 700 | 1 | |a Heidari, Arash |e verfasserin |4 aut | |
| 700 | 1 | |a Petersen, Greti |e verfasserin |4 aut | |
| 700 | 1 | |a Sabetian, Katayoun |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of investigative medicine high impact case reports |d 2013 |g 9(2021) vom: 01. Jan., Seite 23247096211028078 |w (DE-627)NLM240776232 |x 2324-7096 |7 nnns |
| 773 | 1 | 8 | |g volume:9 |g year:2021 |g day:01 |g month:01 |g pages:23247096211028078 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1177/23247096211028078 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 9 |j 2021 |b 01 |c 01 |h 23247096211028078 | ||