Hypoxemia During One-Lung Ventilation : Does It Really Matter?

© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021..

PURPOSE OF REVIEW: Hypoxemia during one-lung ventilation, while decreasing in frequency, persists as an intraoperative challenge for anesthesiologists. Discerning when desaturation and resultant hypoxemia correlates to tissue hypoxia is challenging in the perioperative setting and requires a thorough understanding of the physiology of oxygen delivery and tissue utilization.

RECENT FINDINGS: Oxygen delivery is not directly correlated with peripheral oxygen saturation in patients undergoing one-lung ventilation, emphasizing the importance of hemoglobin concentration and cardiac output in avoiding tissue hypoxia. While healthy humans can tolerate acute hypoxemia without long-term consequences, there is a paucity of evidence from patients undergoing thoracic surgery. Increasingly recognized is the potential harm of hyperoxic states, particularly in the setting of complex patients with comorbid diseases.

SUMMARY: Anesthesiologists are left to determine an acceptable oxygen saturation nadir that is individualized to the patient and procedure based on an understanding of oxygen supply, demand, and the consequences of interventions.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:11

Enthalten in:

Current anesthesiology reports - 11(2021), 4 vom: 12., Seite 414-420

Sprache:

Englisch

Beteiligte Personen:

Durkin, Chris [VerfasserIn]
Romano, Kali [VerfasserIn]
Egan, Sinead [VerfasserIn]
Lohser, Jens [VerfasserIn]

Links:

Volltext

Themen:

Hypoxemia
Hypoxia
Journal Article
One-lung ventilation
Oxygen delivery
Review
Thoracic anesthesia

Anmerkungen:

Date Revised 01.11.2022

published: Print-Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.1007/s40140-021-00470-5

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM327997788