Pneumocystis Pneumonia in a Patient with Ovarian Cancer Receiving Olaparib Therapy
We herein report a case of pneumocystis pneumonia (PCP) in a 77-year-old woman with ovarian cancer who was receiving olaparib therapy. After the patient's second relapse of ovarian cancer, she was administered olaparib as maintenance therapy following successful completion of docetaxel and carboplatin therapy. On receiving olaparib, she showed symptoms of a fever and malaise. Based on laboratory and imaging findings, she was diagnosed with PCP. After treatment with corticosteroids and trimethoprim/sulfamethoxazole followed by atovaquone, the patient's general condition improved. The lymphocytopenia observed after olaparib administration may have been associated with the development of PCP.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:61 |
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| Enthalten in: |
Internal medicine (Tokyo, Japan) - 61(2022), 2 vom: 15. Jan., Seite 217-221 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Himeji, Daisuke [VerfasserIn] |
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| Links: |
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| Themen: |
Case Reports |
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| Anmerkungen: |
Date Completed 18.01.2022 Date Revised 10.03.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.2169/internalmedicine.7485-21 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM327939451 |
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| 520 | |a We herein report a case of pneumocystis pneumonia (PCP) in a 77-year-old woman with ovarian cancer who was receiving olaparib therapy. After the patient's second relapse of ovarian cancer, she was administered olaparib as maintenance therapy following successful completion of docetaxel and carboplatin therapy. On receiving olaparib, she showed symptoms of a fever and malaise. Based on laboratory and imaging findings, she was diagnosed with PCP. After treatment with corticosteroids and trimethoprim/sulfamethoxazole followed by atovaquone, the patient's general condition improved. The lymphocytopenia observed after olaparib administration may have been associated with the development of PCP | ||
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| 700 | 1 | |a Matsumoto, Ryoichi |e verfasserin |4 aut | |
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| 700 | 1 | |a Taniguchi, Shuichi |e verfasserin |4 aut | |
| 700 | 1 | |a Moriguchi, Sayaka |e verfasserin |4 aut | |
| 700 | 1 | |a Marutsuka, Kousuke |e verfasserin |4 aut | |
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