Risk Factors for Development of Endophthalmitis after Open Globe Injury in Children : A Case-Control Study
AIM: To identify risk-factors for developing endophthalmitis following open globe injury (OGI) in children.
METHODS: Retrospective, single-center, case-control study of children aged <18 years who sustained OGI.
RESULTS: Our cohort of 93 eyes consisted of 30 cases (Group A- endophthalmitis) and 63 controls (Group B- no endophthalmitis). Twenty-four eyes (80%) diagnosed with endophthalmitis presented after 24 hours of injury. The presence of central corneal zone-1 injuries (Odd ratio [OR]: 6.64, p= 0.001) and vitreous in wound (OR: 3.53) were associated with the risk of developing endophthalmitis. (p= < 0.05) Additionally the presence of iris prolapse (OR: 4.76) and posterior capsular rupture (PCR) (OR: 5.80) increased the risk of developing endophthalmitis.(p <0.05) . Streptococci was isolated in 15 eyes, Pseudomonas in 3 eyes, and Candida in 1 eye. The visual outcomes at three months were significantly worse in Group A (LogMAR 1.77±1.06) compared to Group B (LogMAR 0.65±0.68)(p<0.05).
CONCLUSION: Central corneal involvement, vitreous/ iris incarceration and PCR were important risk factors for development of PTE in children.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
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| Enthalten in: |
Ocular immunology and inflammation - 30(2022), 7-8 vom: 03. Okt., Seite 1633-1638 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sen, Pradhnya [VerfasserIn] |
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| Links: |
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| Themen: |
Endophthalmitis |
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| Anmerkungen: |
Date Completed 15.12.2022 Date Revised 15.12.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1080/09273948.2021.1928237 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM327874708 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a AIM: To identify risk-factors for developing endophthalmitis following open globe injury (OGI) in children | ||
| 520 | |a METHODS: Retrospective, single-center, case-control study of children aged <18 years who sustained OGI | ||
| 520 | |a RESULTS: Our cohort of 93 eyes consisted of 30 cases (Group A- endophthalmitis) and 63 controls (Group B- no endophthalmitis). Twenty-four eyes (80%) diagnosed with endophthalmitis presented after 24 hours of injury. The presence of central corneal zone-1 injuries (Odd ratio [OR]: 6.64, p= 0.001) and vitreous in wound (OR: 3.53) were associated with the risk of developing endophthalmitis. (p= < 0.05) Additionally the presence of iris prolapse (OR: 4.76) and posterior capsular rupture (PCR) (OR: 5.80) increased the risk of developing endophthalmitis.(p <0.05) . Streptococci was isolated in 15 eyes, Pseudomonas in 3 eyes, and Candida in 1 eye. The visual outcomes at three months were significantly worse in Group A (LogMAR 1.77±1.06) compared to Group B (LogMAR 0.65±0.68)(p<0.05) | ||
| 520 | |a CONCLUSION: Central corneal involvement, vitreous/ iris incarceration and PCR were important risk factors for development of PTE in children | ||
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