Longitudinal study of serpiginous choroiditis and serpiginous like choroiditis using wide field OCT angiography
PURPOSE: To assess the ability of wide field Swept Source OCTA (SS-OCTA) imaging to detect morphological variations in Serpiginous Choroiditis (SC) and Serpiginous Like Choroiditis (SLC) in response to treatment and also analyze these findings quantitatively using Image J software.
METHODS: Retrospective observational case series of nine eyes with clinical diagnosis of active SC and SLC, who underwent SS-OCTA and fundus autofluorescence (FAF) imaging at baseline and each follow up visit till 6 months. Morphological analysis was done by two independent graders and quantitative analysis to measure the size and intensity of lesion was done using publicly available Image J software at baseline and each follow up visit.
DESIGN: Retrospective observational case series.
RESULTS: Using SS-OCTA, all the active lesions followed a characteristic healing pattern. Active lesions appear well defined hypo flow void patches and as healing progressed, lesion became more ill-defined and iso-hyper- intense. Significant increase in mean intensity of the lesion could be apparent after 1 and 6 month of treatment. There was reduction in the size of lesions during follow up however this difference was not statistically significant.
CONCLUSION: SS-OCTA could be a useful noninvasive tool to study the treatment response in SC/SLC both morphologically as well as quantitatively. Quantitative parameters need to be designed in further research studies to aid in uniform management and follow up of uveitis cases.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:32 |
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| Enthalten in: |
European journal of ophthalmology - 32(2022), 3 vom: 06. Mai, Seite 1555-1561 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Brar, Manpreet [VerfasserIn] |
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| Links: |
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| Themen: |
Choroidal/retinal inflammation |
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| Anmerkungen: |
Date Completed 17.05.2022 Date Revised 17.05.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1177/11206721211028529 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM327273194 |
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| 100 | 1 | |a Brar, Manpreet |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Longitudinal study of serpiginous choroiditis and serpiginous like choroiditis using wide field OCT angiography |
| 264 | 1 | |c 2022 | |
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| 500 | |a Date Completed 17.05.2022 | ||
| 500 | |a Date Revised 17.05.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a PURPOSE: To assess the ability of wide field Swept Source OCTA (SS-OCTA) imaging to detect morphological variations in Serpiginous Choroiditis (SC) and Serpiginous Like Choroiditis (SLC) in response to treatment and also analyze these findings quantitatively using Image J software | ||
| 520 | |a METHODS: Retrospective observational case series of nine eyes with clinical diagnosis of active SC and SLC, who underwent SS-OCTA and fundus autofluorescence (FAF) imaging at baseline and each follow up visit till 6 months. Morphological analysis was done by two independent graders and quantitative analysis to measure the size and intensity of lesion was done using publicly available Image J software at baseline and each follow up visit | ||
| 520 | |a DESIGN: Retrospective observational case series | ||
| 520 | |a RESULTS: Using SS-OCTA, all the active lesions followed a characteristic healing pattern. Active lesions appear well defined hypo flow void patches and as healing progressed, lesion became more ill-defined and iso-hyper- intense. Significant increase in mean intensity of the lesion could be apparent after 1 and 6 month of treatment. There was reduction in the size of lesions during follow up however this difference was not statistically significant | ||
| 520 | |a CONCLUSION: SS-OCTA could be a useful noninvasive tool to study the treatment response in SC/SLC both morphologically as well as quantitatively. Quantitative parameters need to be designed in further research studies to aid in uniform management and follow up of uveitis cases | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Choroidal/retinal inflammation | |
| 650 | 4 | |a Serpiginous choroiditis | |
| 650 | 4 | |a Swept source OCT Angiography | |
| 650 | 4 | |a serpiginous like choroiditis | |
| 700 | 1 | |a Sharma, Mansi |e verfasserin |4 aut | |
| 700 | 1 | |a Grewal, Sps |e verfasserin |4 aut | |
| 700 | 1 | |a Grewal, Dilraj |e verfasserin |4 aut | |
| 700 | 1 | |a Dogra, Mangat Ram |e verfasserin |4 aut | |
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