Comparison of three embolic materials at partial splenic artery embolization for hypersplenism : clinical, laboratory, and radiological outcomes
PURPOSE: To compare effectiveness of three widely used embolic agents in partial splenic embolization (PSE) by analyzing their clinical, laboratory, and radiological outcomes within one year of follow-up.
MATERIALS AND METHODS: This retrospective study examined 179 patients who underwent PSE to manage hypersplenism secondary to cirrhosis. Patients were divided into 3 groups according to embolic agent used. Group 1 (gelatin sponge) included 65 patients, group 2 (embospheres) included 58 patients, and group 3 (PVA) included 56 patients. Clinical, laboratory, and radiological outcomes were compared between groups.
RESULTS: The technical success rate was 100% in all groups. Pain as a major complication was lower in the gelatin sponge group (20%) compared to the embosphere group (31%) and PVA group (32.3%). Major complications other than pain were found in 20.1%; 24.6% in gelatin sponge group, 15.5% in embosphere group and 19.6% in PVA group (p = 0.045). WBCs and platelet counts showed a significant increase after PSE in all groups. Entire splenic volume as measured by computed tomography after PSE showed no significant difference among the 3 groups; however, the volume of infarcted spleen was significantly lower in the gelatin sponge group compared to other two groups (p = 0.001). The splenic span was significantly reduced one-year post-procedure in three groups (p = 0.006), and it was significantly less in embosphere and PVA groups compared to gelatin sponge group (p < 0.05). Recurrent bleeding was higher in gelatin sponge group (p < 0.05).
CONCLUSIONS: Permanent embolic materials achieved better laboratory and radiological outcomes than gelatin sponge particles in PSE of cirrhotic hypersplenism patients. However, permanent particles were associated with greater abdominal pain.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
|---|---|
| Enthalten in: |
Insights into imaging - 12(2021), 1 vom: 26. Juni, Seite 85 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Zaitoun, Mohamed M A [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Embolization (therapeutic) |
|---|
| Anmerkungen: |
Date Revised 10.07.2021 published: Electronic Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.1186/s13244-021-01030-5 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM327209739 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM327209739 | ||
| 003 | DE-627 | ||
| 005 | 20231226203220.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1186/s13244-021-01030-5 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1090.xml |
| 035 | |a (DE-627)NLM327209739 | ||
| 035 | |a (NLM)34173891 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Zaitoun, Mohamed M A |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Comparison of three embolic materials at partial splenic artery embolization for hypersplenism |b clinical, laboratory, and radiological outcomes |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 10.07.2021 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a PURPOSE: To compare effectiveness of three widely used embolic agents in partial splenic embolization (PSE) by analyzing their clinical, laboratory, and radiological outcomes within one year of follow-up | ||
| 520 | |a MATERIALS AND METHODS: This retrospective study examined 179 patients who underwent PSE to manage hypersplenism secondary to cirrhosis. Patients were divided into 3 groups according to embolic agent used. Group 1 (gelatin sponge) included 65 patients, group 2 (embospheres) included 58 patients, and group 3 (PVA) included 56 patients. Clinical, laboratory, and radiological outcomes were compared between groups | ||
| 520 | |a RESULTS: The technical success rate was 100% in all groups. Pain as a major complication was lower in the gelatin sponge group (20%) compared to the embosphere group (31%) and PVA group (32.3%). Major complications other than pain were found in 20.1%; 24.6% in gelatin sponge group, 15.5% in embosphere group and 19.6% in PVA group (p = 0.045). WBCs and platelet counts showed a significant increase after PSE in all groups. Entire splenic volume as measured by computed tomography after PSE showed no significant difference among the 3 groups; however, the volume of infarcted spleen was significantly lower in the gelatin sponge group compared to other two groups (p = 0.001). The splenic span was significantly reduced one-year post-procedure in three groups (p = 0.006), and it was significantly less in embosphere and PVA groups compared to gelatin sponge group (p < 0.05). Recurrent bleeding was higher in gelatin sponge group (p < 0.05) | ||
| 520 | |a CONCLUSIONS: Permanent embolic materials achieved better laboratory and radiological outcomes than gelatin sponge particles in PSE of cirrhotic hypersplenism patients. However, permanent particles were associated with greater abdominal pain | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Embolization (therapeutic) | |
| 650 | 4 | |a Gelatin sponge (absorbable) | |
| 650 | 4 | |a Hypersplenism | |
| 650 | 4 | |a Polyvinyl alcohol | |
| 650 | 4 | |a Trisacryl gelatin microspheres | |
| 700 | 1 | |a Basha, Mohammad Abd Alkhalik |e verfasserin |4 aut | |
| 700 | 1 | |a Elsayed, Saeed Bakry |e verfasserin |4 aut | |
| 700 | 1 | |a El Deen, Dalia Salah |e verfasserin |4 aut | |
| 700 | 1 | |a Zaitoun, Nahla A |e verfasserin |4 aut | |
| 700 | 1 | |a Alturkistani, Husain |e verfasserin |4 aut | |
| 700 | 1 | |a Farag, Alaa A |e verfasserin |4 aut | |
| 700 | 1 | |a Abdelsalam, Hassan |e verfasserin |4 aut | |
| 700 | 1 | |a El-Kenawy, Hossam A |e verfasserin |4 aut | |
| 700 | 1 | |a Mahmoud, Nader E M |e verfasserin |4 aut | |
| 700 | 1 | |a Alayouty, Nader Ali |e verfasserin |4 aut | |
| 700 | 1 | |a Eladl, Ibrahim M |e verfasserin |4 aut | |
| 700 | 1 | |a Shahin, Shahenda |e verfasserin |4 aut | |
| 700 | 1 | |a Almarzooqi, Mohamed-Karji |e verfasserin |4 aut | |
| 700 | 1 | |a Hendi, Ali M |e verfasserin |4 aut | |
| 700 | 1 | |a El-Morsy, Ahmad |e verfasserin |4 aut | |
| 700 | 1 | |a Elmokadem, Ali Hassan |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Insights into imaging |d 2010 |g 12(2021), 1 vom: 26. Juni, Seite 85 |w (DE-627)NLM218604823 |x 1869-4101 |7 nnns |
| 773 | 1 | 8 | |g volume:12 |g year:2021 |g number:1 |g day:26 |g month:06 |g pages:85 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1186/s13244-021-01030-5 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 12 |j 2021 |e 1 |b 26 |c 06 |h 85 | ||