Organocatalytic Strategies for the Development of the Enantioselective Inverse-electron-demand Hetero-Diels-Alder Reaction

© 2021 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH..

Cycloaddition reactions, in particular Diels-Alder reactions, have attracted a lot of attention from organic chemists since they represent one of the most powerful methodologies for the construction of carbon-carbon bonds. In particular, inverse-electron-demand hetero-Diels-Alder reactions have been an important breakthrough for the synthesis of heterocyclic compounds. Among all their variants, the organocatalytic enantioselective version has been widely explored since the asymmetric construction of diversely functionalized scaffolds under reaction conditions encompassed within the green chemistry field is of great interest. In this review, a profound revision on the latest advances on the organocatalytic asymmetric inverse-electron demand hetero-Diels-Alder reaction is shown.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

Chemistry (Weinheim an der Bergstrasse, Germany) - 27(2021), 49 vom: 01. Sept., Seite 12509-12520

Sprache:

Englisch

Beteiligte Personen:

Laina-Martín, Víctor [VerfasserIn]
Fernández-Salas, Jose A [VerfasserIn]
Alemán, José [VerfasserIn]

Links:

Volltext

Themen:

Asymmetric synthesis
Cycloadditions
Diels-Alder
Heterocycles
Heterocyclic Compounds
Journal Article
Organocatalysis
Review

Anmerkungen:

Date Completed 02.09.2021

Date Revised 29.09.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/chem.202101696

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM32680059X