Epidemiology and prognosis of patients with a history of cancer admitted to intensive care. A multicenter observational study
Copyright © 2021. Published by Elsevier España, S.L.U..
OBJECTIVE: To assess the epidemiology and outcome at discharge of cancer patients requiring admission to the Intensive Care Unit (ICU).
DESIGN: A descriptive observational study was made of data from the ENVIN-HELICS registry, combined with specifically compiled variables. Comparisons were made between patients with and without neoplastic disease, and groups of cancer patients with a poorer outcome were identified.
SETTING: Intensive Care Units participating in ENVIN-HELICS 2018, with voluntary participation in the oncological registry.
PATIENTS: Subjects admitted during over 24 h and diagnosed with cancer in the last 5 years.
PRIMARY ENDPOINTS: The general epidemiological endpoints of the ENVIN-HELICS registry and cancer-related variables.
RESULTS: Of the 92 ICUs with full data, a total of 11,796 patients were selected, of which 1786 (15.1%) were cancer patients. The proportion of cancer patients per Unit proved highly variable (1%-48%). In-ICU mortality was higher among the cancer patients than in the non-oncological subjects (12.3% versus 8.9%; p < .001). Elective postoperative (46.7%) or emergency admission (15.3%) predominated in the cancer patients. Patients with medical disease were in more serious condition, with longer stay and greater mortality (27.5%). The patients admitted to the ICU due to nonsurgical disease related to cancer exhibited the highest mortality rate (31.4%).
CONCLUSIONS: Great variability was recorded in the percentage of cancer patients in the different ICUs. A total of 46.7% of the patients were admitted after undergoing scheduled surgery. The highest mortality rate corresponded to patients with medical disease (27.5%), and to those admitted due to cancer-related complications (31.4%).
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:45 |
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| Enthalten in: |
Medicina intensiva - 45(2021), 6 vom: 20. Aug., Seite 332-346 |
| Sprache: |
Englisch |
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| Links: |
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| Themen: |
Epidemiología |
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| Anmerkungen: |
Date Completed 25.11.2021 Date Revised 25.11.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.medine.2021.05.003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM326751807 |
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| 024 | 7 | |a 10.1016/j.medine.2021.05.003 |2 doi | |
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| 041 | |a eng | ||
| 100 | 1 | |a Olaechea Astigarraga, P M |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Epidemiology and prognosis of patients with a history of cancer admitted to intensive care. A multicenter observational study |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 25.11.2021 | ||
| 500 | |a Date Revised 25.11.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021. Published by Elsevier España, S.L.U. | ||
| 520 | |a OBJECTIVE: To assess the epidemiology and outcome at discharge of cancer patients requiring admission to the Intensive Care Unit (ICU) | ||
| 520 | |a DESIGN: A descriptive observational study was made of data from the ENVIN-HELICS registry, combined with specifically compiled variables. Comparisons were made between patients with and without neoplastic disease, and groups of cancer patients with a poorer outcome were identified | ||
| 520 | |a SETTING: Intensive Care Units participating in ENVIN-HELICS 2018, with voluntary participation in the oncological registry | ||
| 520 | |a PATIENTS: Subjects admitted during over 24 h and diagnosed with cancer in the last 5 years | ||
| 520 | |a PRIMARY ENDPOINTS: The general epidemiological endpoints of the ENVIN-HELICS registry and cancer-related variables | ||
| 520 | |a RESULTS: Of the 92 ICUs with full data, a total of 11,796 patients were selected, of which 1786 (15.1%) were cancer patients. The proportion of cancer patients per Unit proved highly variable (1%-48%). In-ICU mortality was higher among the cancer patients than in the non-oncological subjects (12.3% versus 8.9%; p < .001). Elective postoperative (46.7%) or emergency admission (15.3%) predominated in the cancer patients. Patients with medical disease were in more serious condition, with longer stay and greater mortality (27.5%). The patients admitted to the ICU due to nonsurgical disease related to cancer exhibited the highest mortality rate (31.4%) | ||
| 520 | |a CONCLUSIONS: Great variability was recorded in the percentage of cancer patients in the different ICUs. A total of 46.7% of the patients were admitted after undergoing scheduled surgery. The highest mortality rate corresponded to patients with medical disease (27.5%), and to those admitted due to cancer-related complications (31.4%) | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Epidemiology | |
| 650 | 4 | |a Epidemiología | |
| 650 | 4 | |a Intensive care unit | |
| 650 | 4 | |a Mortalidad | |
| 650 | 4 | |a Mortality rate | |
| 650 | 4 | |a Oncological patients | |
| 650 | 4 | |a Paciente oncológico | |
| 650 | 4 | |a Unidad de cuidados intensivos | |
| 700 | 1 | |a Álvarez Lerma, F |e verfasserin |4 aut | |
| 700 | 1 | |a Beato Zambrano, C |e verfasserin |4 aut | |
| 700 | 1 | |a Gimeno Costa, R |e verfasserin |4 aut | |
| 700 | 1 | |a Gordo Vidal, F |e verfasserin |4 aut | |
| 700 | 1 | |a Durá Navarro, R |e verfasserin |4 aut | |
| 700 | 1 | |a Ruano Suarez, C |e verfasserin |4 aut | |
| 700 | 1 | |a Aldabó Pallás, T |e verfasserin |4 aut | |
| 700 | 1 | |a Garnacho Montero, J |e verfasserin |4 aut | |
| 700 | 0 | |a ENVIN-HELICS Study Group |e verfasserin |4 aut | |
| 700 | 0 | |a List of supervisors and units participating in the ONCOENVIN study, ordered by number of patients contributed to the epidemiological study |e verfasserin |4 aut | |
| 700 | 1 | |a Durá Navarro, Raquel |e investigator |4 oth | |
| 700 | 1 | |a Ruano Suarez, María Carmen |e investigator |4 oth | |
| 700 | 1 | |a Alonso Araujo, Inmaculada |e investigator |4 oth | |
| 700 | 1 | |a Arenzana Seisdedos, Ángel |e investigator |4 oth | |
| 700 | 1 | |a Córdoba López, Alberto |e investigator |4 oth | |
| 700 | 1 | |a Camino Redondo, Nuria |e investigator |4 oth | |
| 700 | 1 | |a Barbadillo Ansorregui, Sandra |e investigator |4 oth | |
| 700 | 1 | |a Mouriz Fernández, Lorena |e investigator |4 oth | |
| 700 | 1 | |a Vilas Otero, Maria Elena |e investigator |4 oth | |
| 700 | 1 | |a Márquez Alonso, José Antonio |e investigator |4 oth | |
| 700 | 1 | |a Bueno Blázquez, Adoración Gema |e investigator |4 oth | |
| 700 | 1 | |a Abella Alvarez, Ana |e investigator |4 oth | |
| 700 | 1 | |a Lobo Palanco, Joaquín |e investigator |4 oth | |
| 700 | 1 | |a Cofiño Castañeda, Luis |e investigator |4 oth | |
| 700 | 1 | |a Montejo González, J C |e investigator |4 oth | |
| 700 | 1 | |a García García, Miguel Ángel |e investigator |4 oth | |
| 700 | 1 | |a Sandar Núñez, María Dolores |e investigator |4 oth | |
| 700 | 1 | |a Tebar Soto, María Teresa |e investigator |4 oth | |
| 700 | 1 | |a Cabadas Avión, Rafael |e investigator |4 oth | |
| 700 | 1 | |a Gimeno Costa, Ricardo |e investigator |4 oth | |
| 700 | 1 | |a Berezo García, José Ángel |e investigator |4 oth | |
| 700 | 1 | |a García López, Fernando |e investigator |4 oth | |
| 700 | 1 | |a López Matamala, Blanca |e investigator |4 oth | |
| 700 | 1 | |a Colomar Ferrá, Asunción |e investigator |4 oth | |
| 700 | 1 | |a Rey García, María Sopetrán |e investigator |4 oth | |
| 700 | 1 | |a Cidoncha Calderón, Belén |e investigator |4 oth | |
| 700 | 1 | |a Alcántara Carmona, Sara |e investigator |4 oth | |
| 700 | 1 | |a Manteiga Riestra, Eva |e investigator |4 oth | |
| 700 | 1 | |a Gil Rueda, Bernardo |e investigator |4 oth | |
| 700 | 1 | |a Gallego González, Carlos |e investigator |4 oth | |
| 700 | 1 | |a Jiménez Sánchez, Roberto |e investigator |4 oth | |
| 700 | 1 | |a de Toro Martín-Consuegra, Ismael López |e investigator |4 oth | |
| 700 | 1 | |a Souto Higueras, Jessica |e investigator |4 oth | |
| 700 | 1 | |a Lander Azcona, Arantxa |e investigator |4 oth | |
| 700 | 1 | |a Fuster Lozano, José María |e investigator |4 oth | |
| 700 | 1 | |a Vera Artázcoz, Paula |e investigator |4 oth | |
| 700 | 1 | |a Castro Orjales, María José |e investigator |4 oth | |
| 700 | 1 | |a Arquitecto Marcide, H |e investigator |4 oth | |
| 700 | 1 | |a Asensio Martín, María José |e investigator |4 oth | |
| 700 | 1 | |a Estecha Foncea, María Antonia |e investigator |4 oth | |
| 700 | 1 | |a Reig Valero, Roberto |e investigator |4 oth | |
| 700 | 1 | |a Priego Sanz, Jesús |e investigator |4 oth | |
| 700 | 1 | |a Vallés Daunis, Jordi |e investigator |4 oth | |
| 700 | 1 | |a Ezpeleta Galindo, Ana Isabel |e investigator |4 oth | |
| 700 | 1 | |a Álvarez Martínez, Braulio |e investigator |4 oth | |
| 700 | 1 | |a Bobillo de Lamo, Felipe |e investigator |4 oth | |
| 700 | 1 | |a Margarit Ribas, Antoni |e investigator |4 oth | |
| 700 | 1 | |a Olaechea Astigarraga, Pedro M |e investigator |4 oth | |
| 700 | 1 | |a Ballesteros Herráez, Juan Carlos |e investigator |4 oth | |
| 700 | 1 | |a Saldaña Fernández, María Teresa |e investigator |4 oth | |
| 700 | 1 | |a Sánchez Miralles, Ángel |e investigator |4 oth | |
| 700 | 1 | |a Amaya Villar, Rosario |e investigator |4 oth | |
| 700 | 1 | |a López-Cuervo, Juan Fajardo |e investigator |4 oth | |
| 700 | 1 | |a Socias, Antonia |e investigator |4 oth | |
| 700 | 1 | |a Bonet Saris, Alfons |e investigator |4 oth | |
| 700 | 1 | |a Díaz Lamas, Ana María |e investigator |4 oth | |
| 700 | 1 | |a Iruretagoyena Amiano, José Ramón |e investigator |4 oth | |
| 700 | 1 | |a Acosta Rivera, Ingrid |e investigator |4 oth | |
| 700 | 1 | |a Cerón García, María |e investigator |4 oth | |
| 700 | 1 | |a Moradillo González, Susana |e investigator |4 oth | |
| 700 | 1 | |a Rodríguez Pedreira, Paula |e investigator |4 oth | |
| 700 | 1 | |a Palencia Herrejón, Eduardo |e investigator |4 oth | |
| 700 | 1 | |a López Núñez, Carlos |e investigator |4 oth | |
| 700 | 1 | |a Mas Lodo, Margarita |e investigator |4 oth | |
| 700 | 1 | |a Pardo Talavera, Juan Carlos |e investigator |4 oth | |
| 700 | 1 | |a Luisa Mora, María |e investigator |4 oth | |
| 700 | 1 | |a Ferrer Roca, Ricard |e investigator |4 oth | |
| 700 | 1 | |a de La Fuente Óconnor, Eugenia |e investigator |4 oth | |
| 700 | 1 | |a Sánchez García, Miguel |e investigator |4 oth | |
| 700 | 1 | |a Blanco Huelga, Carmen |e investigator |4 oth | |
| 700 | 1 | |a Garijo Catalina, María Ángeles |e investigator |4 oth | |
| 700 | 1 | |a Alcalá López, Adoración |e investigator |4 oth | |
| 700 | 1 | |a Ugalde Gutierrez, Marta |e investigator |4 oth | |
| 700 | 1 | |a Navarro Ruiz, María Rosa |e investigator |4 oth | |
| 700 | 1 | |a Román Millan, María José |e investigator |4 oth | |
| 700 | 1 | |a Lara Aguayo, Pedro |e investigator |4 oth | |
| 700 | 1 | |a Herreros Gonzalo, María |e investigator |4 oth | |
| 700 | 1 | |a Claverias Cabrera, Laura |e investigator |4 oth | |
| 700 | 1 | |a Martos López, José |e investigator |4 oth | |
| 700 | 1 | |a Valdovinos Mahave, María Concepción |e investigator |4 oth | |
| 700 | 1 | |a Fontaneda López, Daniel |e investigator |4 oth | |
| 700 | 1 | |a Matachana Martínez, María |e investigator |4 oth | |
| 700 | 1 | |a García Sánchez, Esther |e investigator |4 oth | |
| 700 | 1 | |a Santarrufina Lluch, Carmen |e investigator |4 oth | |
| 700 | 1 | |a Garcés González, Rafael |e investigator |4 oth | |
| 700 | 1 | |a Gallego Lara, Sonia |e investigator |4 oth | |
| 700 | 1 | |a Martinez Trivez, Pilar |e investigator |4 oth | |
| 700 | 1 | |a Vilanova Pàmies, Cecília |e investigator |4 oth | |
| 700 | 1 | |a Llanos Jorge, Celina |e investigator |4 oth | |
| 700 | 1 | |a Asensio Martín, María José |e investigator |4 oth | |
| 700 | 1 | |a Montejo Gonzalez, Juan Carlos |e investigator |4 oth | |
| 700 | 1 | |a Alemparte Pardavila, Enrique |e investigator |4 oth | |
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